Drug Interaction Report
3 potential interactions and/or warnings found for the following 2 drugs:
- Bicillin C-R 900/300 (penicillin g benzathine / procaine penicillin)
- omadacycline
Interactions between your drugs
procaine penicillin omadacycline
Applies to: Bicillin C-R 900/300 (penicillin g benzathine / procaine penicillin), omadacycline
Consumer information for this interaction is not currently available.
GENERALLY AVOID: Tetracyclines may reduce the effect of penicillins by inhibiting cellular protein synthesis which is necessary for cell wall synthesis inhibition by penicillins. Antagonism is more likely when low doses of either agent are administered. Therapeutic failure may result.
MANAGEMENT: This combination should be avoided if possible.
penicillin G benzathine omadacycline
Applies to: Bicillin C-R 900/300 (penicillin g benzathine / procaine penicillin), omadacycline
Consumer information for this interaction is not currently available.
GENERALLY AVOID: Tetracyclines may reduce the effect of penicillins by inhibiting cellular protein synthesis which is necessary for cell wall synthesis inhibition by penicillins. Antagonism is more likely when low doses of either agent are administered. Therapeutic failure may result.
MANAGEMENT: This combination should be avoided if possible.
Drug and food interactions
omadacycline food
Applies to: omadacycline
Do not take iron supplements, multivitamins, calcium supplements, or antacids within 4 hours before or after taking omadacycline. These products can make omadacycline less effective in treating your infection. Omadacycline should be taken at least 2 hours before (4 hours for dairy products) or 4 hours after meals. Dairy products can make it harder for your body to absorb the medication.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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