Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- droxidopa
- Urolene Blue (methylene blue)
Interactions between your drugs
methylene blue droxidopa
Applies to: Urolene Blue (methylene blue), droxidopa
GENERALLY AVOID: Based on their mechanism of action, nonselective monoamine oxidase inhibitors (MAOIs) may potentiate the risk of supine hypertension associated with the use of droxidopa in the treatment of neurogenic orthostatic hypotension.
MANAGEMENT: Concomitant use of droxidopa with nonselective MAOIs or other agents that possess MAOI activity (e.g., furazolidone, linezolid, methylene blue, procarbazine) should be avoided. Selective MAO-B inhibitors such as rasagiline and selegiline were permitted in droxidopa clinical trials.
References (1)
- (2014) "Product Information. Northera (droxidopa)." Chelsea Therapeutics Inc
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Northera
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Ephedrine
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Phenylephrine
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Further information
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