Drug Interaction Report

Ask your doctor before using edrophonium together with atropine. Using these medications together can cause increasing muscle weakness. In addition, such use may mask the less serious, gastrointestinal signs of atropine overdose and lead to difficulty breathing, chest pain, and possibly death. If your doctor prescribes these medications together, you may need a dose adjustment or special tests to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Using fludrocortisone together with edrophonium may result in severe muscle weakness in patients with myasthenia gravis. If you have been receiving treatment with edrophonium, you may experience increased muscle weakness when fludrocortisone is first initiated. Improvement in muscular function may occur gradually. Talk to your doctor if you have any questions or concerns. Your doctor may discontinue edrophonium at least one day before you start taking fludrocortisone. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Ask your doctor before using atropine together with ethanol (alcohol). Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking atropine. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.