Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- epoetin beta-methoxy polyethylene glycol
- lovotibeglogene autotemcel
Interactions between your drugs
epoetin beta-methoxy polyethylene glycol lovotibeglogene autotemcel
Applies to: epoetin beta-methoxy polyethylene glycol, lovotibeglogene autotemcel
GENERALLY AVOID: Erythropoiesis-stimulating agents (ESAs) may interfere with the efficacy and manufacturing of the autologous hematopoietic stem cell-based gene therapy, lovotibeglogene autotemcel. The exact mechanism has not been fully described in product labeling or clinical studies. Data regarding the use of ESAs between apheresis and myeloablative conditioning as well as after the lovotibeglogene autotemcel infusion are unavailable.
MANAGEMENT: The manufacturer of lovotibeglogene autotemcel recommends discontinuing the use of erythropoiesis-stimulating agents at least 2 months prior to the initiation of HSC mobilization. The manufacturer does not provide guidance on the use of erythropoiesis-stimulating agents after apheresis and before myeloablative conditioning, or after the lovotibeglogene autotemcel infusion.
References (1)
- (2023) "Product Information. Lyfgenia (lovotibeglogene autotemcel)." bluebird bio
Drug and food/lifestyle interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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