Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- Bactroban (mupirocin topical)
- simeprevir
Interactions between your drugs
No drug ⬌ drug interactions were found between the drugs in your list. However, this does not necessarily mean no drug interactions exist. Always consult your healthcare provider.
Drug and food interactions
simeprevir food
Applies to: simeprevir
ADJUST DOSING INTERVAL: Food significantly enhances the oral bioavailability of simeprevir, although the type of food does not seem to matter. In healthy study subjects, administration of simeprevir after a high-fat, high-caloric (928 kcal) breakfast increased systemic exposure (AUC) by 61% and delayed absorption by 1 hour, while administration after a normal caloric (533 kcal) breakfast increased AUC by 69% and delayed absorption by 1.5 hours.
MANAGEMENT: To ensure maximal oral absorption, simeprevir should be administered with food.
References (1)
- (2013) "Product Information. Olysio (simeprevir)." Janssen Pharmaceuticals
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Report options
- Switch to consumer interaction data
- Email this report to a friend, doctor, or patient
- Ask questions, find answers
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Rifadin
Rifadin is used for bartonellosis, endocarditis, haemophilus influenzae prophylaxis, legionella ...
Centany
Centany is used for impetigo, nasal carriage of staphylococcus aureus, secondary cutaneous ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Flagyl
Flagyl is used to treat bacterial infections of the vagina, stomach, skin and joints. Learn about ...
Zosyn
Zosyn is used to treat bacterial infections such as urinary tract and skin infections and ...
Cleocin
Cleocin (clindamycin) is used to treat serious bacterial infections. Includes Cleocin side effects ...
Unasyn
Unasyn is used for aspiration pneumonia, bacterial infection, bone infection, deep neck infection ...
Cefoxitin
Cefoxitin is used for aspiration pneumonia, bacterial infection, bone infection, cesarean section ...
Cilastatin/imipenem
Cilastatin/imipenem is used for aspiration pneumonia, bacteremia, bacterial infection, bone ...
Ampicillin/sulbactam
Ampicillin/sulbactam is used for aspiration pneumonia, bacterial infection, bone infection, deep ...
Learn more
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.