Drug Interaction Report

Talk to your doctor before using apomorphine together with paliperidone. Combining these medications may decrease the effectiveness of apomorphine. In addition, the risk of side effects such as drowsiness, dizziness, lightheadedness, low blood pressure, and irregular heartbeat may also increase. You should avoid activities requiring mental alertness until you know how these medications affect you. If you experience increased episodes of falling asleep during normal daily activities, you should avoid driving and other potentially hazardous activities until you have been evaluated by your doctor. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Alcohol can lower your blood pressure and add to the effects of apomorphine. Drinking alcohol while taking apomorphine may decrease your blood pressure and cause drowsiness. This can cause nausea, extreme drowsiness, slow heartbeat, headaches, and dizziness. If you take apomorphine with alcohol tell your doctor if you have any of these symptoms. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

You should avoid the use of alcohol while being treated with paliperidone. Alcohol can increase the nervous system side effects of paliperidone such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. Paliperidone may be taken with or without food. Talk to your doctor or pharmacist if you have any questions or concerns.