Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- Crestor (rosuvastatin)
- medroxyprogesterone
Interactions between your drugs
medroxyPROGESTERone rosuvastatin
Applies to: medroxyprogesterone, Crestor (rosuvastatin)
Coadministration with rosuvastatin may increase the plasma concentrations of certain oral contraceptive hormones. The mechanism of interaction has not been established. According to the manufacturer, concomitant use of rosuvastatin and an oral contraceptive resulted in an increase in ethinyl estradiol and norgestrel area under the plasma concentration-time curve (AUC) of 26% and 34%, respectively. The clinical significance of these alterations is unknown but should be considered when selecting oral contraceptive doses.
References (1)
- (2003) "Product Information. Crestor (rosuvastatin)." AstraZeneca Pharma Inc
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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