Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- Ethezyme 650 (papain/urea topical)
- silver topical
Interactions between your drugs
papain topical silver topical
Applies to: Ethezyme 650 (papain/urea topical), silver topical
GENERALLY AVOID: Papain may be inactivated by the salts of heavy metals such as lead, silver, and mercury. The mechanism of interaction has not been described.
MANAGEMENT: Topical preparations containing heavy metals such as lead, silver, and mercury should not be used on wounds treated with papain.
References (4)
- (2004) "Product Information. Accuzyme (papain-urea topical)." Healthpoint
- (2005) "Product Information. Ethezyme (papain-urea topical)." Ethex Corporation
- (2007) "Product Information. Panafil (chlorophyllin copper com/papain/urea topical)." Healthpoint Ltd
- (2007) "Product Information. Ziox (chlorophyllin copper com/papain/urea topical)." Stratus Pharmaceuticals Inc
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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