Drug Interaction Report
4 potential interactions and/or warnings found for the following 2 drugs:
- pancrelipase
- Rolaids Advanced (calcium carbonate / magnesium hydroxide / simethicone)
Interactions between your drugs
calcium carbonate pancrelipase
Applies to: Rolaids Advanced (calcium carbonate / magnesium hydroxide / simethicone), pancrelipase
Using calcium carbonate together with pancrelipase can decrease the effects of pancrelipase. Calcium carbonate and pancrelipase doses should be separated by at least one hour. Contact your doctor if your condition worsens. You may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
magnesium hydroxide pancrelipase
Applies to: Rolaids Advanced (calcium carbonate / magnesium hydroxide / simethicone), pancrelipase
Using magnesium hydroxide together with pancrelipase can decrease the effects of pancrelipase. Magnesium hydroxide and pancrelipase doses should be separated by at least one hour. Contact your doctor if your condition worsens. You may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
calcium carbonate food
Applies to: Rolaids Advanced (calcium carbonate / magnesium hydroxide / simethicone)
Calcium absorption may be increased by taking it with food. However, foods high in oxalic acid (spinach or rhubarb), or phytic acid (bran and whole grains) may decrease calcium absorption. Calcium may be taken with food to increase absorption. Consider spacing calcium administration for at least 2 hours before or after consuming foods high in oxalic acid or phytic acid. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
pancrelipase food
Applies to: pancrelipase
Pancrelipase may reduce the effectiveness of folic acid and iron by interfering with their absorption. To prevent or minimize the interaction, you should separate the dosing times of pancrelipase and any product containing folic acid or iron by as much as possible. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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