Drug Interaction Report

Using magnesium sulfate together with magnesium oxide can lead to elevated magnesium blood levels, particularly in people with reduced kidney function. Symptoms of high magnesium levels may include nausea, vomiting, flushing, drowsiness, dizziness, confusion, muscle weakness, reduced reflexes, low blood pressure, slow heart rate, and impaired breathing. You should seek medical attention if you experience these symptoms. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Oral medications may not be properly absorbed when they are taken within one hour before starting sodium picosulfate for bowel cleansing. Talk to your doctor or pharmacist to see if you should adjust the dosing schedule of your other medications before you begin bowel cleansing treatment. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

The recommended maximum number of medicines in the 'magnesium' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'magnesium' category:

• magnesium sulfate
• Prepopik (citric acid/magnesium oxide/sodium picosulfate)

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.