Drug Interaction Report

Tiludronate and magnesium sulfate should not be taken orally at the same time. Products that contain magnesium, aluminum, calcium, iron, and/or other minerals may interfere with the absorption of tiludronate into the bloodstream and reduce its effectiveness. You should take magnesium sulfate at least 2 hours before or 2 hours after the tiludronate dose. Talk to a healthcare professional if you are not sure whether a product contains something that could potentially interact with your medication or if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Food significantly decreases the levels of tiludronate. Tiludronate should be administered on an empty stomach with 6 to 8 ounces of plain water at least 2 hours before or 2 hours after food. This will make it easier for your body to absorb the medication.