Drug Interaction Report
6 potential interactions and/or warnings found for the following 2 drugs:
- aluminum carbonate
- Tussirex (codeine / pheniramine / phenylephrine / sodium citrate)
Interactions between your drugs
aluminum carbonate sodium citrate
Applies to: aluminum carbonate, Tussirex (codeine / pheniramine / phenylephrine / sodium citrate)
Ask your doctor before using aluminum carbonate together with sodium citrate. Using these medications together can increase the effects of aluminum carbonate which could result in too high of aluminum blood levels. If you have end-stage renal disease you are particularly at risk of developing high aluminum blood levels and encephalopathy (brain disease). You should separate doses of aluminum carbonate and sodium citrate by 2 to 3 hours. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
codeine pheniramine
Applies to: Tussirex (codeine / pheniramine / phenylephrine / sodium citrate), Tussirex (codeine / pheniramine / phenylephrine / sodium citrate)
Using codeine together with pheniramine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
aluminum carbonate food
Applies to: aluminum carbonate
Citrate, or citric acid, can increase the absorption of aluminum carbonate. This may lead to elevated blood levels of aluminum, particularly in individuals with reduced kidney function, since aluminum is primarily eliminated by the kidneys. Excess aluminum may deposit and cause problems in various tissues including bone, brain, heart, liver, muscles, and spleen. Over time, weak bones, bone pain, fractures, skeletal deformity, brain disorders, and anemia may develop. Talk to your doctor before using aluminum carbonate if you have kidney impairment or are on hemodialysis. You should avoid or limit the consumption of citrate-containing foods and beverages (e.G., soft drinks, citrus fruits, fruit juices) during treatment with aluminum carbonate. Be aware that some effervescent and dispersible drug formulations may also contain citrate and should be restricted as well. Even if you do not have kidney problems, it may be best to separate the dosing of aluminum carbonate and citrate-containing products by 2 to 3 hours. Talk to a healthcare professional if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
When aluminum carbonate is taken during enteral nutrition therapy (tube feeding), the tube may get clogged. Therefore, aluminum carbonate should not be mixed with or given after high-protein tube feedings. The dose should be separated from the feeding by as much as possible, and the tube should be thoroughly flushed before administration of the dose.
pheniramine food
Applies to: Tussirex (codeine / pheniramine / phenylephrine / sodium citrate)
Alcohol can increase the nervous system side effects of pheniramine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with pheniramine. Do not use more than the recommended dose of pheniramine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
codeine food
Applies to: Tussirex (codeine / pheniramine / phenylephrine / sodium citrate)
Do not use alcohol or medications that contain alcohol while you are receiving treatment with codeine. This may increase nervous system side effects such as drowsiness, dizziness, lightheadedness, difficulty concentrating, and impairment in thinking and judgment. In severe cases, low blood pressure, respiratory distress, fainting, coma, or even death may occur. With certain long-acting formulations of narcotic pain medication, consumption of alcohol may also cause rapid release of the drug, resulting in high blood levels that may be potentially lethal. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. Do not use more than the recommended dose of codeine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.
phenylephrine food
Applies to: Tussirex (codeine / pheniramine / phenylephrine / sodium citrate)
Both phenylephrine and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
See also:
Pepcid
Pepcid is used to treat ulcers in the stomach and for conditions where the stomach produces too ...
Prilosec
Prilosec (omeprazole) is used to treat symptoms of GERD and other conditions caused by excess ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Pepto-Bismol
Pepto-Bismol is antacid used to treat heart burn, indigestion, diarrhea, gas or an upset stomach ...
Zantac
Zantac is used to treat and prevent ulcers in the stomach and intestines. Includes Zantac side ...
Milk of Magnesia
Milk of Magnesia is used for acne, constipation, indigestion
Pepcid AC
Pepcid AC is used for duodenal ulcer, duodenal ulcer prophylaxis, erosive esophagitis, GERD ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.