Drug Interaction Report

The injection of steroids together with radiocontrast dyes into the spine is not recommended, as it may increase the risk of seizures, meningitis, and inflammation of the spinal membranes. They may be given together by other routes.

Grapefruit juice may increase the blood levels of certain medications such as methylPREDNISolone. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with methylPREDNISolone. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.