Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- Florinef (fludrocortisone)
- ProAmatine (midodrine)
Interactions between your drugs
fludrocortisone midodrine
Applies to: Florinef (fludrocortisone), ProAmatine (midodrine)
MONITOR: Although midodrine is often used with fludrocortisone (with or without salt supplementation) for the treatment of orthostatic hypotension, this combination may lead to excessive increases in blood pressure and intraocular pressure. Glaucoma may be aggravated in some patients.
MANAGEMENT: Caution is advised, especially in patients with ocular diseases. Blood pressure and intraocular pressure should be monitored during concomitant use. Prior to initiating treatment with midodrine it may be prudent to decrease the dose of fludrocortisone or decrease the patient's salt intake.
References (1)
- (2001) "Product Information. ProAmatine (midodrine)." Roberts Pharmaceutical Corporation
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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