Somatrogon and Alcohol/Food Interactions
There are 2 alcohol/food/lifestyle interactions with somatrogon.
Somatrogon Obesity
Major Potential Hazard, Moderate plausibility
human growth hormone - Prader-Willi Syndrome
Somatropin and somatrogon is contraindicated in patients with Prader-Willi Syndrome who are severely obese, have a history of upper airway obstruction or sleep apnea, or have severe respiratory impairment. There have been reports of sudden death when somatropin was used in such patients.
References (4)
- (2004) "Product Information. Serostim (somatropin)." Serono Laboratories Inc
- (2004) "Product Information. Zorbtive (somatropin)." Serono Laboratories Inc
- (2021) "Product Information. Skytrofa (lonapegsomatropin)." Ascendis Pharma, Inc.
- (2023) "Product Information. Ngenla (somatrogon)." Pfizer U.S. Pharmaceuticals Group
Somatrogon Obesity
Moderate Potential Hazard, Moderate plausibility
somatrogon - diabetes mellitus
Treatment with growth hormone may decrease insulin sensitivity, inducing a state of insulin resistance and hyperglycemia, especially at higher doses. New onset type 2 diabetes mellitus (DM) or worsened glycemic control in patients with undiagnosed pre-diabetes or DM has been reported in patients receiving growth hormone. Monitor glucose levels in all patients during therapy with somatrogon, especially in those with who have glucose intolerance, or additional risk factors for diabetes (e.g., obesity, Turner syndrome, family history). Initiation of somatrogon in patients who have type 1 or 2 diabetes mellitus may require dose adjustment of anti-diabetic therapy.
References (1)
- (2023) "Product Information. Ngenla (somatrogon)." Pfizer U.S. Pharmaceuticals Group
Switch to consumer interaction data
Somatrogon drug interactions
There are 437 drug interactions with somatrogon.
Somatrogon disease interactions
There are 8 disease interactions with somatrogon which include:
- active malignancy
- acute critical illness
- diabetic retinopathy
- Prader-Willi Syndrome
- intracranial hypertension
- scoliosis
- diabetes mellitus
- Turner syndrome
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- Drug class: growth hormones
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Ngenla
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Humatrope
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Sogroya
Sogroya information from Drugs.com, includes Sogroya side effects, interactions and indications.
Skytrofa
Skytrofa injection is a once-weekly, slow-release human growth hormone (lonapegsomatropin) ...
Genotropin
Genotropin is a human growth hormone used to treat growth failure in children and adults who lack ...
Norditropin
Norditropin is used to treat growth hormone deficiency (GHD) in adults and children and other ...
Omnitrope
Omnitrope (somatropin) is a form of human growth hormone used to treat adults and children with ...
Norditropin FlexPro
Norditropin FlexPro is used for adult human growth hormone deficiency, idiopathic short stature ...
Zomacton
Zomacton is used for adult human growth hormone deficiency, idiopathic short stature, pediatric ...
Nutropin AQ
Nutropin AQ (somatropin) is an injectable preparation that may be used to treat children with ...
Further information
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