Orap (pimozide) and Alcohol / Food Interactions
There are 2 alcohol/food/lifestyle interactions with Orap (pimozide) which include:
Caffeine ↔ pimozide
Moderate Drug Interaction
Using caffeine together with pimozide may increase the levels of pimozide and affect the rhythm of your heart. Contact your doctor if you experience irregular heartbeat, chest tightness, blurred vision or nausea. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
pimozide ↔ food
Major Food Interaction
You should avoid the consumption of large amounts of grapefruits and grapefruit juice while taking pimozide. Grapefruit can raise the levels of pimozide in your body. This can affect the rhythm of your heart and cause other side effects. Call your doctor if you have symptoms of blurred vision or nausea. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or fast or pounding heartbeats during treatment with pimozide. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. You should avoid or limit the use of alcohol while being treated with pimozide. Alcohol can increase the nervous system side effects of pimozide such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. Talk to your doctor or pharmacist if you have any questions or concerns.
Orap (pimozide) drug Interactions
There are 1023 drug interactions with Orap (pimozide)
Orap (pimozide) disease Interactions
There are 18 disease interactions with Orap (pimozide) which include:
- Cns Depression/Coma
- Previous Neuroleptic Malignant Syndrome (Nms)
- Seizure Disorders
- Acute Alcohol Intoxication
- Cns Depression
- Tardive Dyskinesia
- Pituitary Tumors
- Qt Interval Prolongation
- Hyperprolactinemia/Breast Cancer
- Anticholinergic Effects
- Seizure Disorders
- Renal/Liver Disease
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
|Major||Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderate||Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minor||Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
Do not stop taking any medications without consulting your healthcare provider.
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