Glycopyrrolate/neostigmine and Alcohol/Food Interactions
There are 3 alcohol/food/lifestyle interactions with glycopyrrolate / neostigmine.
Neostigmine Alcohol (Ethanol)
Moderate Drug Interaction
Ask your doctor before using neostigmine together with glycopyrrolate. Using these medications together can cause increasing muscle weakness. In addition, such use may mask the less serious, gastrointestinal signs of glycopyrrolate overdose and lead to difficulty breathing, chest pain, and possibly death. If your doctor prescribes these medications together, you may need a dose adjustment or special tests to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Glycopyrrolate Alcohol (Ethanol)
Moderate Drug Interaction
Ask your doctor before using glycopyrrolate together with ethanol (alcohol). Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking glycopyrrolate. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
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Glycopyrrolate High Blood Pressure (Hypertension)
Minor Potential Hazard, Moderate plausibility
anticholinergics - hypertension
Cardiovascular effects of anticholinergics may exacerbate hypertension. Therapy with anticholinergic agents should be administered cautiously in patients with hypertension.
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Glycopyrrolate/neostigmine drug interactions
There are 278 drug interactions with glycopyrrolate / neostigmine.
Glycopyrrolate/neostigmine disease interactions
There are 21 disease interactions with glycopyrrolate / neostigmine which include:
- arrhythmias
- autonomic neuropathy
- GI obstruction
- glaucoma
- obstructive uropathy
- tardive dyskinesia
- infectious diarrhea
- bradycardia
- coronary artery disease
- parkinsonism
- myasthenia gravis
- ulcerative colitis
- intestinal/urinary obstruction
- psychoses
- hyperthyroidism
- Down's syndrome
- liver impairment
- renal impairment
- hepatic impairment
- hypertension
- fever
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More about glycopyrrolate / neostigmine
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- Dosage information
- During pregnancy
- Drug class: antidotes
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Prostigmin Bromide
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Sugammadex
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Neostigmine
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
