Leqselvi and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Leqselvi (deuruxolitinib).
Deuruxolitinib Food/Lifestyle
Moderate Food Interaction
MONITOR: Smoking during treatment with deuruxolitinib may increase the risk of major adverse cardiovascular events (MACE) and the risk of developing malignancies. In clinical studies of deuruxolitinib, individuals who were current or former smokers had an additional increased risk of overall malignancies. Also, deuruxolitinib may increase patients' risk of MACE, including myocardial infarction, stroke, and cardiovascular death.
MANAGEMENT: Caution is advised if deuruxolitinib is prescribed to current or past smokers. Patients should be informed about the symptoms of serious cardiovascular events and the steps to take if they occur. The manufacturer recommends discontinuing deuruxolitinib in patients that have experienced a myocardial infarction or stroke. Deuruxolitinib may be taken with or without food.
References (1)
- (2024) "Product Information. Leqselvi (deuruxolitinib)." Sun Pharmaceutical Industries
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Leqselvi drug interactions
There are 336 drug interactions with Leqselvi (deuruxolitinib).
Leqselvi disease interactions
There are 8 disease interactions with Leqselvi (deuruxolitinib) which include:
- infections
- cardiovascular risk
- malignancy
- thrombosis
- cytopenias
- gastrointestinal perforation
- liver dysfunction
- renal dysfunction
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- Drug class: multikinase inhibitors
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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