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Vyleesi and Alcohol/Food Interactions

There are 2 alcohol/food/lifestyle interactions with Vyleesi (bremelanotide).


Bremelanotide Food

Moderate Food Interaction

Bremelanotide may affect the absorption of other medications that you take by mouth. In some cases, this may affect how well and/or how fast those medications work, or it may make no difference. If you are taking oral medications that depend on adequate blood levels to be effective (e.G., antibiotics) or oral medications that require a rapid onset of effect (e.G., pain medications), it is recommended that you avoid using bremelanotide. Talk to a healthcare provider if you have any questions or concerns, and contact your doctor if your symptoms worsen or your condition changes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Bremelanotide High Blood Pressure (Hypertension)

Major Potential Hazard, Moderate plausibility

bremelanotide - hypertension/CV disease

Bremelanotide is contraindicated in patients who have uncontrolled hypertension or known cardiovascular disease, as it transiently increases blood pressure and reduces heart rate after each dose. Before initiating bremelanotide, and periodically during treatment, consider the patient's cardiovascular risk and ensure blood pressure is well-controlled.


  1. (2019) "Product Information. Vyleesi (bremelanotide)." AMAG Pharmaceuticals Inc

Vyleesi drug interactions

There is 1 drug interaction with Vyleesi (bremelanotide).

Vyleesi disease interactions

There are 3 disease interactions with Vyleesi (bremelanotide) which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.