Arbutamine and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with arbutamine.
Arbutamine High Blood Pressure (Hypertension)
Major Potential Hazard, Moderate plausibility
dobutamine/arbutamine - arrhythmias
Dobutamine and arbutamine produce stimulation of the beta receptors of the heart. The use of these agents has been associated with an increase in heart rate, ventricular ectopy, atrial fibrillation, hypertension, enhanced A-V conduction, and arrhythmias. Therapy with dobutamine or arbutamine should be administered cautiously in patients with cardiac conduction disorders.
References (10)
- Bianchi C, Diaz R, Gonzales C, Beregovich J (1975) "Effects of dobutamine on atrioventricular conduction." Am Heart J, 90, p. 474-8
- (2002) "Product Information. Dobutrex (dobutamine)." Lilly, Eli and Company
- Baudhuin T, Marwick T, Melin J, Wijns W, D'Hondt AM, Detry JM (1993) "Diagnosis of coronary artery disease in elderly patients: safety and efficacy of dobutamine echocardiography." Eur Heart J, 14, p. 799-803
- Poldermans D, Fioretti PM, Boersma E, Forster T, Vanurk H, Cornel JH, Arnese M, Roelandt JRTC (1994) "Safety of dobutamine-atropine stress echocardiography in patients with suspected or proven coronary artery disease." Am J Cardiol, 73, p. 456-9
- Picano E, Mathias W, Pingitore A, Bigi R, Previtali M (1994) "Safety and tolerability of dobutamine-atropine stress echocardiography: a prospective, multicentre study." Lancet, 344, p. 1190-2
- Kinder C, Chamberlain J, Kall J, Kopp D, Johnson M, Costanzo MR, Wilber D (1994) "Prognostic significance of sustained ventricular tachyarrhythmia occurring during dobutamine infusion." J Heart Lung Transplant, 13, p. 1045-50
- Cohen A, Chauvel C, Benhalima B, Blanchard B (1995) "Complication of dobutamine stress echocardiography." Lancet, 345, p. 201-2
- Tisdale JE, Patel R, Webb CR, Borzak S, Zarowitz BJ (1995) "Electrophysiologic and proarrhythmic effects of intravenous inotropic agents." Prog Cardiovasc Dis, 38, p. 167-80
- Previtali M, Lanzarini L, Fetiveau R, Poli A, Diotallevi P (1996) "Dobutamine-induced and spontaneous sustained ventricular tachycardia in recent myocardial infarction." Eur Heart J, 17, p. 803-4
- (2001) "Product Information. GenESA (arbutamine)." Gensia Inc
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Arbutamine drug interactions
There are 68 drug interactions with arbutamine.
Arbutamine disease interactions
There are 3 disease interactions with arbutamine which include:
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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