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Abacavir and Alcohol/Food Interactions

There are 3 alcohol/food/lifestyle interactions with abacavir.

Minor

Alcohol (Ethanol) abacavir

Minor Drug Interaction

Information for this minor interaction is available on the professional version.

Moderate

High Blood Pressure (Hypertension)

Moderate Potential Hazard, Moderate plausibility

abacavir - cardiovascular disease

Some clinical trials have reported increased risk of myocardial infarction in patients treated with abacavir. Although some of the findings are inconclusive, as a precaution, the underlying risk of coronary heart disease should be assessed before therapy, and action should be taken to minimize all modifiable risk factors such as hypertension, hyperlipidemia, diabetes mellitus, smoking, etc.

References

  1. "Product Information. Ziagen (abacavir)." Glaxo Wellcome (2001):
Moderate

High Cholesterol (Hyperlipoproteinemia, Hypertriglyceridemia, Sitosterolemia)

Moderate Potential Hazard, Moderate plausibility

abacavir - cardiovascular disease

Some clinical trials have reported increased risk of myocardial infarction in patients treated with abacavir. Although some of the findings are inconclusive, as a precaution, the underlying risk of coronary heart disease should be assessed before therapy, and action should be taken to minimize all modifiable risk factors such as hypertension, hyperlipidemia, diabetes mellitus, smoking, etc.

References

  1. "Product Information. Ziagen (abacavir)." Glaxo Wellcome (2001):

Abacavir drug interactions

There are 44 drug interactions with abacavir.

Abacavir disease interactions

There are 2 disease interactions with abacavir which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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