Sotorasib Drug Interactions
Currently displaying a list of 503 drugs known to interact with sotorasib.
- 114 major drug interactions
- 374 moderate drug interactions
- 15 minor drug interactions
Medications known to interact with sotorasib
Note: Showing generic names only.
A
- abemaciclib
- acalabrutinib
- afatinib
- albendazole
- alfentanil
- aliskiren
- alpelisib
- alprazolam
- aluminum carbonate
- aluminum hydroxide
- ambrisentan
- aminoglutethimide
- amiodarone
- amlodipine
- amobarbital
- amprenavir
- apalutamide
- apixaban
- apremilast
- aprepitant
- aripiprazole
- armodafinil
- artesunate
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- astemizole
- atazanavir
- atezolizumab
- atogepant
- atorvastatin
- atrasentan
- avacopan
- avanafil
- avapritinib
- avatrombopag
- avelumab
- axitinib
B
- bedaquiline
- belumosudil
- belzutifan
- bepridil
- berotralstat
- betamethasone
- betrixaban
- bexarotene
- black cohosh
- boceprevir
- bortezomib
- bosentan
- bosutinib
- brentuximab
- brexpiprazole
- brigatinib
- bromocriptine
- budesonide
- buprenorphine
- buspirone
- butabarbital
- butalbital
- butorphanol
C
- cabazitaxel
- cabozantinib
- calaspargase pegol
- calcium carbonate
- cannabidiol
- capivasertib
- capmatinib
- carbamazepine
- cariprazine
- caspofungin
- cemiplimab
- cenobamate
- ceritinib
- cerivastatin
- cevimeline
- chlorotrianisene
- cimetidine
- cisapride
- cladribine
- clarithromycin
- clofarabine
- clonazepam
- clorazepate
- cobicistat
- cobimetinib
- codeine
- colchicine
- conivaptan
- conjugated estrogens
- copanlisib
- cortisone
- cosibelimab
- crinecerfont
- crizotinib
- cyclosporine
D
- dabigatran
- dabrafenib
- daclatasvir
- daclizumab
- dapsone topical
- daridorexant
- darifenacin
- darolutamide
- darunavir
- dasatinib
- deferasirox
- deflazacort
- dehydroepiandrosterone
- delafloxacin
- delavirdine
- deucravacitinib
- dexamethasone
- dexlansoprazole
- dienestrol topical
- digoxin
- dihydroergotamine
- dihydroxyaluminum sodium carbonate
- disopyramide
- docetaxel
- dofetilide
- dolutegravir
- donepezil
- doravirine
- dostarlimab
- doxazosin
- doxercalciferol
- doxorubicin
- doxorubicin liposomal
- dronedarone
- droperidol
- drospirenone
- durvalumab
- dutasteride
- duvelisib
E
- edoxaban
- efavirenz
- elacestrant
- elafibranor
- elagolix
- eletriptan
- eliglustat
- elvitegravir
- encorafenib
- enfortumab vedotin
- entrectinib
- enzalutamide
- epirubicin
- eplerenone
- erdafitinib
- ergonovine
- ergotamine
- erlotinib
- erythromycin
- eslicarbazepine
- esomeprazole
- estazolam
- esterified estrogens
- estradiol
- estradiol topical
- estrone
- estropipate
- estropipate topical
- eszopiclone
- ethinyl estradiol
- ethosuximide
- etonogestrel
- etoposide
- etravirine
- everolimus
- exemestane
F
- famotidine
- fedratinib
- felbamate
- felodipine
- fenfluramine
- fentanyl
- fesoterodine
- fexinidazole
- fexofenadine
- fidaxomicin
- finerenone
- flibanserin
- fludrocortisone
- flurazepam
- fosamprenavir
- fosaprepitant
- fosphenytoin
- fostamatinib
- fostemsavir
- fruquintinib
G
- ganaxolone
- gefitinib
- gepirone
- gilteritinib
- glasdegib
- glycerol phenylbutyrate
- granisetron
- griseofulvin
- guanfacine
H
I
- ibrexafungerp
- ibrutinib
- idarubicin
- idelalisib
- imatinib
- indinavir
- infigratinib
- interferon beta-1a
- interferon beta-1b
- ipilimumab
- iptacopan
- irinotecan
- irinotecan liposomal
- isavuconazonium
- isotretinoin
- isradipine
- istradefylline
- itraconazole
- ivabradine
- ivacaftor
- ivermectin
- ivosidenib
- ixabepilone
- ixazomib
K
L
- lacosamide
- lansoprazole
- lapatinib
- larotrectinib
- lazertinib
- lefamulin
- leflunomide
- lemborexant
- lenacapavir
- leniolisib
- lesinurad
- letrozole
- levamlodipine
- levobupivacaine
- levoketoconazole
- levomethadyl acetate
- levonorgestrel
- lidocaine
- linagliptin
- lomitapide
- lonafarnib
- lonapegsomatropin
- loperamide
- loratadine
- lorlatinib
- lovastatin
- lumateperone
- lurasidone
- lurbinectedin
- lusutrombopag
M
- macimorelin
- macitentan
- magaldrate
- magnesium carbonate
- magnesium hydroxide
- magnesium oxide
- maraviroc
- maribavir
- mavacamten
- mavorixafor
- medroxyprogesterone
- mefloquine
- megestrol
- mephobarbital
- methadone
- methotrexate
- methylergonovine
- methylprednisolone
- methysergide maleate
- metreleptin
- mibefradil
- midazolam
- midostaurin
- mifepristone
- mipomersen
- mirabegron
- mirtazapine
- mitapivat
- mitotane
- mitoxantrone
- mobocertinib
- modafinil
- montelukast
- morphine
N
- nafcillin
- naldemedine
- naloxegol
- naltrexone
- nefazodone
- nelfinavir
- neratinib
- nevirapine
- nicardipine
- nifedipine
- nilotinib
- nimodipine
- nintedanib
- niraparib
- nirogacestat
- nisoldipine
- nitisinone
- nivolumab
- nizatidine
- norethindrone
- norgestrel
O
- olaparib
- oliceridine
- olutasidenib
- omaveloxolone
- omeprazole
- ondansetron
- oritavancin
- osilodrostat
- osimertinib
- oxcarbazepine
- oxybutynin
- oxycodone
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- palbociclib
- palovarotene
- panobinostat
- pantoprazole
- paricalcitol
- pazopanib
- pegaspargase
- peginterferon beta-1a
- pembrolizumab
- pemigatinib
- pentobarbital
- perampanel
- pexidartinib
- phenobarbital
- phenylbutazone
- phenytoin
- pimavanserin
- pimozide
- pirtobrutinib
- pitolisant
- pomalidomide
- ponatinib
- posaconazole
- pralsetinib
- praziquantel
- prednisolone
- prednisone
- pretomanid
- primidone
- progesterone
- progesterone topical
- prucalopride
Q
R
- rabeprazole
- ramelteon
- ranitidine
- ranitidine bismuth citrate
- ranolazine
- red yeast rice
- relugolix
- remdesivir
- repaglinide
- repotrectinib
- retifanlimab
- revumenib
- ribociclib
- rifabutin
- rifampin
- rifapentine
- rifaximin
- rilpivirine
- rimegepant
- riociguat
- ripretinib
- ritlecitinib
- ritonavir
- rivaroxaban
- rolapitant
- romidepsin
- rosuvastatin
- rucaparib
- rufinamide
- ruxolitinib
- ruxolitinib topical
S
- saquinavir
- saxagliptin
- secobarbital
- selexipag
- selpercatinib
- selumetinib
- sildenafil
- silodosin
- simvastatin
- siponimod
- sirolimus
- sirolimus protein-bound
- sodium bicarbonate
- solifenacin
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sonidegib
- sorafenib
- sparsentan
- st. john's wort
- stiripentol
- sufentanil
- sulfasalazine
- sulfinpyrazone
- sunitinib
- suvorexant
- suzetrigine
T
- tacrolimus
- tadalafil
- talazoparib
- tamoxifen
- tamsulosin
- tasimelteon
- tazemetostat
- tecovirimat
- telaprevir
- telithromycin
- telotristat
- temsirolimus
- teniposide
- tenofovir alafenamide
- tenofovir disoproxil
- tepotinib
- terfenadine
- teriflunomide
- testosterone
- testosterone topical
- thioguanine
- thiotepa
- tiagabine
- ticagrelor
- tinidazole
- tipranavir
- tislelizumab
- tofacitinib
- tolvaptan
- topotecan
- toremifene
- toripalimab
- tovorafenib
- trabectedin
- tramadol
- trazodone
- tremelimumab
- tretinoin
- triamcinolone
- triazolam
- trofinetide
- troglitazone
- troleandomycin
- tucatinib
U
V
- valbenazine
- valdecoxib
- vamorolone
- vandetanib
- vemurafenib
- venetoclax
- verapamil
- vibegron
- vilazodone
- vinblastine
- vincristine
- vincristine liposome
- vinorelbine
- voclosporin
- vonoprazan
- vorapaxar
- vorasidenib
- voriconazole
- vortioxetine
- voxelotor
W
Z
Sotorasib alcohol/food interactions
There is 1 alcohol/food interaction with sotorasib.
Sotorasib disease interactions
There is 1 disease interaction with sotorasib which include:
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More about sotorasib
- sotorasib consumer information
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- Drug class: miscellaneous antineoplastics
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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