Can you take Omeprazole with Sebex?
1 drug interaction and 4 additional warnings found for the following 2 drugs:
- omeprazole
- Sebex (salicylic acid/sulfur topical)
Drug interactions
Moderate drug interactions
Moderate:
salicylic acid topical sulfur topical
Applies to: Sebex (salicylic acid/sulfur topical) and Sebex (salicylic acid/sulfur topical)
Application of salicylic acid topical and sulfur topical to the same areas may cause excessive irritation or drying of the skin. Your healthcare provider may be able to prescribe alternatives that do not interact. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Food/lifestyle interactions
No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Disease interactions
4 potential interactions Applies to: 4 conditions, including Osteoporosis, Diarrhea, Pseudomembranous Colitis, and Magnesium Imbalance.
Diarrhea
Major:
omeprazole
Omeprazole has a major potential interaction with Diarrhea.
Published observational studies suggest that proton pump inhibitor (PPI) use may be associated with an increased risk of Clostridium difficile-associated diarrhea (CDAD), especially in hospitalized patients. This diagnosis should be considered for diarrhea that does not improve. It is recommended that patients should use the lowest dose and shortest duration of PPI therapy appropriate to the condition being treated. Close monitoring is recommended in patients with diarrhea and in those taking antibacterial agents as CDAD has been reported with the use of nearly all these agents. Treatment with antibacterial agents alters the normal flora of the colon, leading to overgrowth of C. difficile. C. difficile produces toxins A and B, which contribute to the development of CDAD. Appropriate fluid and electrolyte management, protein supplementation, antibiotic treatment of C. difficile, and surgical evaluation should be instituted as clinically indicated.
Magnesium Imbalance
Moderate:
omeprazole
Omeprazole has a moderate potential interaction with Magnesium Imbalance.
Symptomatic and asymptomatic hypomagnesemia has been reported rarely in patients treated with PPIs for at least 3 months, in most cases after a year of therapy. Serious adverse events can include tetany, seizures, and arrhythmias. Caution should be used in patients prone to magnesium imbalances such as patients taking other medications that can cause hypomagnesemia (e.g., diuretics). Regular monitoring is recommended.
Osteoporosis
Moderate:
omeprazole
Omeprazole has a moderate potential interaction with Osteoporosis.
Various published observational studies have reported that PPI therapy may be associated with an increased risk for osteoporosis related fractures of the hip, wrist or spine. The risk was increased in patients who received high doses (multiple daily doses), and long term treatment (a year or longer). Patients should use the lowest dose and shortest duration of PPI therapy appropriate to the condition being treated. Caution should be used in patients at risk for osteoporosis related fractures and should be managed according to established treatment guidelines.
Pseudomembranous Colitis
Major:
omeprazole
Omeprazole has a major potential interaction with Pseudomembranous Colitis.
Published observational studies suggest that proton pump inhibitor (PPI) use may be associated with an increased risk of Clostridium difficile-associated diarrhea (CDAD), especially in hospitalized patients. This diagnosis should be considered for diarrhea that does not improve. It is recommended that patients should use the lowest dose and shortest duration of PPI therapy appropriate to the condition being treated. Close monitoring is recommended in patients with diarrhea and in those taking antibacterial agents as CDAD has been reported with the use of nearly all these agents. Treatment with antibacterial agents alters the normal flora of the colon, leading to overgrowth of C. difficile. C. difficile produces toxins A and B, which contribute to the development of CDAD. Appropriate fluid and electrolyte management, protein supplementation, antibiotic treatment of C. difficile, and surgical evaluation should be instituted as clinically indicated.
More resources
omeprazole
A total of 269 drugs are known to interact with omeprazole.
- Omeprazole is in the drug class proton pump inhibitors.
- Omeprazole is used to treat the following conditions:
Sebex
A total of 203 drugs are known to interact with Sebex.
- Sebex is in the drug class miscellaneous topical agents.
- Sebex is used to treat the following conditions:
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.