Orfadin Drug Interactions
Currently displaying a list of 243 drugs known to interact with Orfadin (nitisinone).
- 9 major drug interactions
- 230 moderate drug interactions
- 4 minor drug interactions
Medications known to interact with Orfadin
Note: Showing generic names only.
- abametapir topical
- abiraterone
- acetohexamide
- adagrasib
- adefovir
- aldesleukin
- aminoglutethimide
- amiodarone
- amlodipine
- amobarbital
- amprenavir
- apalutamide
- aprepitant
- armodafinil
- asciminib
- atazanavir
- avacopan
- avatrombopag
- baricitinib
- belzutifan
- berotralstat
- betiatide
- bexarotene
- bicalutamide
- boceprevir
- bosentan
- brigatinib
- bromocriptine
- butabarbital
- butalbital
- capivasertib
- carbamazepine
- carvedilol
- celecoxib
- cenobamate
- ceritinib
- chloramphenicol
- chlorpropamide
- cimetidine
- ciprofloxacin
- clarithromycin
- clofarabine
- clotrimazole
- cobicistat
- conivaptan
- crizotinib
- cyclophosphamide
- cyclosporine
- dabrafenib
- danazol
- dapsone
- daridorexant
- darunavir
- dasatinib
- deferasirox
- delavirdine
- dexamethasone
- diclofenac
- didanosine
- diltiazem
- doxepin
- dronabinol
- dronedarone
- duvelisib
- echinacea
- edaravone
- efavirenz
- elafibranor
- elagolix
- empagliflozin
- encorafenib
- ensifentrine
- entrectinib
- enzalutamide
- erythromycin
- eslicarbazepine
- etravirine
- fedratinib
- felbamate
- fenfluramine
- fexinidazole
- flibanserin
- fluconazole
- fluoxetine
- flurbiprofen
- fluvastatin
- fluvoxamine
- fosamprenavir
- fosaprepitant
- fosphenytoin
- furosemide
- ibuprofen
- idelalisib
- imatinib
- indinavir
- indomethacin
- iptacopan
- irbesartan
- isavuconazonium
- isoniazid
- isotretinoin
- itraconazole
- ivacaftor
- ivosidenib
- lapatinib
- larotrectinib
- lazertinib
- lefamulin
- lenacapavir
- lesinurad
- letermovir
- levamlodipine
- levoketoconazole
- lomitapide
- lonafarnib
- lonapegsomatropin
- lorlatinib
- losartan
- macitentan
- mavacamten
- mavorixafor
- mefenamic acid
- meloxicam
- mephobarbital
- meropenem
- methadone
- methotrexate
- metreleptin
- mibefradil
- micafungin
- mifepristone
- mitapivat
- mitotane
- mobocertinib
- modafinil
- montelukast
- pacritinib
- palbociclib
- paroxetine
- pazopanib
- pentobarbital
- pexidartinib
- phenobarbital
- phenylbutazone
- phenytoin
- pioglitazone
- pirfenidone
- piroxicam
- pirtobrutinib
- pitolisant
- posaconazole
- pralsetinib
- prednisone
- primidone
- ramelteon
- ranolazine
- remdesivir
- repotrectinib
- ribociclib
- rifabutin
- rifampin
- rifapentine
- ritlecitinib
- ritonavir
- rucaparib
- rufinamide
- saquinavir
- secobarbital
- seladelpar
- selpercatinib
- sertraline
- siponimod
- sitagliptin
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sotorasib
- st. john's wort
- stiripentol
- sulfamethoxazole
- sulfinpyrazone
- suprofen ophthalmic
- suvorexant
- suzetrigine
- tamoxifen
- tazemetostat
- tecovirimat
- telaprevir
- telithromycin
- telotristat
- thiopental
- ticagrelor
- ticlopidine
- tolazamide
- tolbutamide
- tolvaptan
- torsemide
- tovorafenib
- treosulfan
- trofinetide
- troglitazone
- troleandomycin
- tucatinib
- vadadustat
- valdecoxib
- vardenafil
- vemurafenib
- verapamil
- viloxazine
- vonoprazan
- vorasidenib
- voriconazole
- voxelotor
Orfadin alcohol/food interactions
There is 1 alcohol/food interaction with Orfadin (nitisinone).
Orfadin disease interactions
There is 1 disease interaction with Orfadin (nitisinone) which include:
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
