Drug interactions between Linzess and Trulance
Interactions between your drugs
- Linzess is in the drug class guanylate cyclase-C agonists.
- Linzess is used to treat the following conditions:
- Trulance is a member of the drug class guanylate cyclase-C agonists.
- Trulance is used to treat the following conditions:
Drug and food interactions
Applies to: Linzess (linaclotide)
Taking linaclotide with food may increase gastrointestinal side effects such as diarrhea, abdominal pain, and gas. The absorption of any other oral medication you may take can be affected if you develop frequent or severe diarrhea. To reduce the risk of gastrointestinal intolerance, linaclotide should be taken on an empty stomach at least 30 minutes prior to the first meal of the day. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.
The recommended maximum number of medicines in the 'gastrointestinal stimulants' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'gastrointestinal stimulants' category:
- linaclotide (active ingredient in Linzess (linaclotide))
- plecanatide (active ingredient in Trulance (plecanatide))
Note: The benefits of taking this combination of medicines may outweigh any risks associated with therapeutic duplication. This information does not take the place of talking to your doctor. Always check with your healthcare provider to determine if any adjustments to your medications are needed.
Drug Interaction Classification
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.