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Drug Interactions between Keppra and Makena

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

No interactions were found between Keppra and Makena. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Keppra

A total of 238 drugs are known to interact with Keppra.

Makena

A total of 212 drugs are known to interact with Makena.

Drug and food interactions

Moderate

HYDROXYprogesterone food

Applies to: Makena (hydroxyprogesterone)

Grapefruit juice may increase the blood levels of certain medications such as HYDROXYprogesterone. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with HYDROXYprogesterone. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.

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Moderate

levETIRAcetam food

Applies to: Keppra (levetiracetam)

Alcohol can increase the nervous system side effects of levETIRAcetam such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with levETIRAcetam. Do not use more than the recommended dose of levETIRAcetam, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

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Moderate

HYDROXYprogesterone food

Applies to: Makena (hydroxyprogesterone)

HYDROXYprogesterone may reduce the blood levels and effects of caffeine. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.