Hydrocodone/phenylephrine Interactions
There are 729 drugs known to interact with hydrocodone/phenylephrine, along with 20 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 231 are major, 495 are moderate, and 3 are minor.
- View all 729 medications that may interact with hydrocodone/phenylephrine
- View hydrocodone/phenylephrine alcohol/food interactions (1)
- View hydrocodone/phenylephrine disease interactions (20)
Most frequently checked interactions
View interaction reports for hydrocodone / phenylephrine and the medicines listed below.
- 5-HTP (5-hydroxytryptophan)
- Adderall XR (amphetamine / dextroamphetamine)
- Advil (ibuprofen)
- Advil Allergy Sinus (chlorpheniramine / ibuprofen / pseudoephedrine)
- Aspirin Low Strength (aspirin)
- Augmentin (amoxicillin / clavulanate)
- Azithromycin Dose Pack (azithromycin)
- B Complex 100 (multivitamin)
- B-Complex SR (multivitamin)
- B-Complex with B-12 (multivitamin)
- Benadryl (diphenhydramine)
- Benicar (olmesartan)
- Breo Ellipta (fluticasone / vilanterol)
- Bydureon (exenatide)
- Calciferol (ergocalciferol)
- Calcium 600 D (calcium / vitamin d)
- Cartia XT (diltiazem)
- Celebrex (celecoxib)
- Cold Multi-Symptom Severe (acetaminophen / dextromethorphan / guaifenesin / phenylephrine)
- CoQ10 (ubiquinone)
- Culturelle Health and Wellness (lactobacillus rhamnosus gg)
- Curcumin 95 (turmeric)
- Cymbalta (duloxetine)
- EpiPen (epinephrine)
- Lipitor (atorvastatin)
- Lyrica (pregabalin)
- Plavix (clopidogrel)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zoloft (sertraline)
Hydrocodone/phenylephrine alcohol/food interactions
There is 1 alcohol/food interaction with hydrocodone / phenylephrine.
Hydrocodone/phenylephrine disease interactions
There are 20 disease interactions with hydrocodone / phenylephrine which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- cardiovascular disease
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
- BPH
- diabetes
- glaucoma
Report options
More about hydrocodone / phenylephrine
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Robitussin Nighttime Cough DM
Robitussin Nighttime Cough DM is used for cough, cough and nasal congestion
Vicks Nyquil Cough
Vicks Nyquil Cough is used for cough, cough and nasal congestion
Dextromethorphan/guaifenesin/phenylephrine
Dextromethorphan/guaifenesin/phenylephrine systemic is used for cough and nasal congestion
Brompheniramine/dextromethorphan/pseudoephedrine
Brompheniramine/dextromethorphan/pseudoephedrine systemic is used for cough and nasal congestion
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.