Hydrocodone / phenylephrine Drug Interactions
A total of 1125 drugs are known to interact with hydrocodone / phenylephrine.
- 440 major drug interactions
- 681 moderate drug interactions
- 4 minor drug interactions
Check for interactions with hydrocodone / phenylephrine
Common medications checked in combination with hydrocodone / phenylephrine
- Aspirin Low Strength (aspirin)
- B Complex 100 (multivitamin)
- B-Complex with B-12 (multivitamin)
- Benicar (olmesartan)
- Calciferol (ergocalciferol)
- Calcium 600 D (calcium / vitamin d)
- Cartia XT (diltiazem)
- Diovan (valsartan)
- Fentanyl Transdermal System (fentanyl)
- ICaps AREDS (multivitamin with minerals)
- Lipitor (atorvastatin)
- Multi-Delyn (multivitamin)
- Nexium (esomeprazole)
- phenylephrine (Sudafed PE Congestion, Neo-Synephrine, Phenyl-T, Nasal Decongestant PE, Vazculep, Suphedrine PE, Help I Have A Stuffy Nose, Despec-SF, Sudogest PE, Nasop12, Triaminic Thin Strips Cold with Stuffy Nose, Dimetapp Toddler's Drops Decongestant, Congest Aid II, AH-Chew D, Gilchew IR, Little Colds Decongestant, Lusonal, Contac-D, Nasop, Ricobid-D, PediaCare Children's Decongestant, Sudafed PE Children's Nasal Decongestant)
- Plavix (clopidogrel)
- Strattera (atomoxetine)
- Tenex (guanfacine)
- Toprol-XL (metoprolol)
- Vitamin C (ascorbic acid)
- Xanax (alprazolam)
- Zoloft (sertraline)
Hydrocodone / phenylephrine alcohol/food interactions
There is 1 alcohol/food interaction with hydrocodone / phenylephrine
Hydrocodone / phenylephrine disease interactions
There are 20 disease interactions with hydrocodone / phenylephrine which include:
- impaired GI motility
- infectious diarrhea
- liver disease
- prematurity
- renal dysfunction
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- cardiovascular disease
- adrenal insufficiency
- biliary spasm
- hypothyroidism
- seizure disorders
- urinary retention
- arrhythmias
- BPH
- diabetes
- glaucoma
More about hydrocodone/phenylephrine
- Hydrocodone/phenylephrine Side Effects
- During Pregnancy
- Dosage Information
- Drug class: upper respiratory combinations
- FDA Alerts (1)
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No information available. |
Do not stop taking any medications without consulting your healthcare provider.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
