Drug Interactions between Envarsus XR and mycophenolate mofetil
This report displays the potential drug interactions for the following 2 drugs:
- Envarsus XR (tacrolimus)
- mycophenolate mofetil
Interactions between your drugs
No interactions were found between Envarsus XR and mycophenolate mofetil. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Envarsus XR
A total of 870 drugs are known to interact with Envarsus XR.
- Envarsus xr is in the drug class calcineurin inhibitors.
- Envarsus xr is used to treat Organ Transplant, Rejection Prophylaxis.
mycophenolate mofetil
A total of 347 drugs are known to interact with mycophenolate mofetil.
- Mycophenolate mofetil is in the drug class selective immunosuppressants.
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Mycophenolate mofetil is used to treat the following conditions:
- Autoimmune Hepatitis (off-label)
- Bullous Pemphigoid (off-label)
- Cogan's Syndrome (off-label)
- Crohn's Disease (off-label)
- Dermatomyositis (off-label)
- Evan's Syndrome (off-label)
- Graft Versus Host Disease (off-label)
- High Cholesterol (off-label)
- Inflammatory Bowel Disease (off-label)
- Linear IgA Disease (off-label)
- Lupus (off-label)
- Lupus Nephritis (off-label)
- Multiple Sclerosis (off-label)
- Myasthenia Gravis (off-label)
- Nephrotic Syndrome (off-label)
- Organ Transplant, Rejection Prophylaxis
- Pemphigoid (off-label)
- Pemphigus (off-label)
- Psoriatic Arthritis (off-label)
- Pulmonary Fibrosis (off-label)
- Rheumatoid Arthritis (off-label)
- Ulcerative Colitis (off-label)
- Uveitis (off-label)
Drug and food interactions
tacrolimus food
Applies to: Envarsus XR (tacrolimus)
ADJUST DOSING INTERVAL: Consumption of food has led to a 27% decrease in the bioavailability of orally administered tacrolimus.
MANAGEMENT: Tacrolimus should be administered at least one hour before or two hours after meals.
GENERALLY AVOID: Grapefruit juice has been reported to increase tacrolimus trough concentrations. Data are limited, but inhibition of the CYP450 enzyme system appears to be involved.
MANAGEMENT: The clinician may want to recommend that the patient avoid ingesting large amounts of grapefruit juice while taking tacrolimus.
References (2)
- (2001) "Product Information. Prograf (tacrolimus)." Fujisawa
- Hooks MA (1994) "Tacrolimus, a new immunosuppressant--a review of the literature." Ann Pharmacother, 28, p. 501-11
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Report options
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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