Dextromethorphan/pseudoephedrine Interactions
There are 527 drugs known to interact with dextromethorphan/pseudoephedrine, along with 6 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 88 are major, 432 are moderate, and 7 are minor.
- View all 527 medications that may interact with dextromethorphan/pseudoephedrine
- View dextromethorphan/pseudoephedrine alcohol/food interactions (1)
- View dextromethorphan/pseudoephedrine disease interactions (6)
Most frequently checked interactions
View interaction reports for dextromethorphan / pseudoephedrine and the medicines listed below.
- Acetylsalicylic Acid (aspirin)
- Acidophilus Probiotic Blend (lactobacillus acidophilus)
- Adult Cold, Flu & Sore Throat (acetaminophen / dextromethorphan / guaifenesin / phenylephrine)
- Artificial Tears (ocular lubricant ophthalmic)
- Co-trimoxazole (sulfamethoxazole / trimethoprim)
- Gardasil 9 (human papillomavirus vaccine)
- Guaifenex (guaifenesin / phenylephrine / phenylpropanolamine)
- Hematinic with Folic Acid (ferrous fumarate/folic acid)
- Hemorrhoidal Ointment (phenylephrine topical)
- Hemorrhoidal Suppositories (starch topical)
- Hyosyne (hyoscyamine)
- IBU (ibuprofen)
- Lyrica (pregabalin)
- Meridia (sibutramine)
- Paracetamol (acetaminophen)
- Tylenol with Codeine (acetaminophen / codeine)
- Valerian Root (valerian)
- Valproate Sodium (valproic acid)
- Vitamin A, D (multivitamin)
- Vitamin B1 (thiamine)
- Vitamin D3 (cholecalciferol)
- Zantac (ranitidine)
Dextromethorphan/pseudoephedrine alcohol/food interactions
There is 1 alcohol/food interaction with dextromethorphan / pseudoephedrine.
Dextromethorphan/pseudoephedrine disease interactions
There are 6 disease interactions with dextromethorphan / pseudoephedrine which include:
More about dextromethorphan / pseudoephedrine
- dextromethorphan/pseudoephedrine consumer information
- Compare alternatives
- Side effects
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
See also:
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Promethazine VC with Codeine is used for cough and nasal congestion
Mucinex D
Mucinex D (guaifenesin and pseudoephedrine) is used to treat nasal and sinus congestion, and to ...
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Robitussin Nighttime Cough DM
Robitussin Nighttime Cough DM is used for cough, cough and nasal congestion
Vicks Nyquil Cough
Vicks Nyquil Cough is used for cough, cough and nasal congestion
Dextromethorphan/guaifenesin/phenylephrine
Dextromethorphan/guaifenesin/phenylephrine systemic is used for cough and nasal congestion
Brompheniramine/dextromethorphan/pseudoephedrine
Brompheniramine/dextromethorphan/pseudoephedrine systemic is used for cough and nasal congestion
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.