Dextromethorphan/pseudoephedrine Interactions
There are 526 drugs known to interact with dextromethorphan/pseudoephedrine, along with 6 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 88 are major, 431 are moderate, and 7 are minor.
- View all 526 medications that may interact with dextromethorphan/pseudoephedrine
- View dextromethorphan/pseudoephedrine alcohol/food interactions (1)
- View dextromethorphan/pseudoephedrine disease interactions (6)
Most frequently checked interactions
View interaction reports for dextromethorphan / pseudoephedrine and the medicines listed below.
- Acetylsalicylic Acid (aspirin)
- Acidophilus Probiotic Blend (lactobacillus acidophilus)
- Adult Cold, Flu & Sore Throat (acetaminophen / dextromethorphan / guaifenesin / phenylephrine)
- Artificial Tears (ocular lubricant ophthalmic)
- Co-trimoxazole (sulfamethoxazole / trimethoprim)
- Gardasil 9 (human papillomavirus vaccine)
- Guaifenex (guaifenesin / phenylephrine / phenylpropanolamine)
- Hematinic with Folic Acid (ferrous fumarate/folic acid)
- Hemorrhoidal Ointment (phenylephrine topical)
- Hemorrhoidal Suppositories (starch topical)
- Hyosyne (hyoscyamine)
- IBU (ibuprofen)
- Lyrica (pregabalin)
- Meridia (sibutramine)
- Paracetamol (acetaminophen)
- Tylenol with Codeine (acetaminophen / codeine)
- Valerian Root (valerian)
- Valproate Sodium (valproic acid)
- Vitamin A, D (multivitamin)
- Vitamin B1 (thiamine)
- Vitamin D3 (cholecalciferol)
- Zantac (ranitidine)
Dextromethorphan/pseudoephedrine alcohol/food interactions
There is 1 alcohol/food interaction with dextromethorphan / pseudoephedrine.
Dextromethorphan/pseudoephedrine disease interactions
There are 6 disease interactions with dextromethorphan / pseudoephedrine which include:
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More about dextromethorphan / pseudoephedrine
- dextromethorphan/pseudoephedrine consumer information
- Compare alternatives
- Side effects
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.