Codeine/pseudoephedrine Interactions
There are 647 drugs known to interact with codeine/pseudoephedrine, along with 22 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 132 are major, 510 are moderate, and 5 are minor.
- View all 647 medications that may interact with codeine/pseudoephedrine
- View codeine/pseudoephedrine alcohol/food interactions (2)
- View codeine/pseudoephedrine disease interactions (22)
Most frequently checked interactions
View interaction reports for codeine / pseudoephedrine and the medicines listed below.
- Augmentin (amoxicillin / clavulanate)
- Augmentin (amoxicillin / clavulanate)
- Imodium A-D (loperamide)
- Imodium A-D (loperamide)
- Paracetamol (acetaminophen)
- Paracetamol (acetaminophen)
- Tramedo (tramadol)
- Tramedo (tramadol)
- Voltaren (diclofenac)
- Voltaren (diclofenac)
- Voltaren Arthritis Pain Gel (diclofenac topical)
- Voltaren Arthritis Pain Gel (diclofenac topical)
Codeine/pseudoephedrine alcohol/food interactions
There are 2 alcohol/food interactions with codeine / pseudoephedrine.
Codeine/pseudoephedrine disease interactions
There are 22 disease interactions with codeine / pseudoephedrine which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- cardiovascular disease
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
- GI narrowing
- PKU
- BPH
- diabetes
- glaucoma
Report options
More about codeine / pseudoephedrine
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Promethazine VC with Codeine
Promethazine VC with Codeine is used for cough and nasal congestion
Mucinex D
Mucinex D (guaifenesin and pseudoephedrine) is used to treat nasal and sinus congestion, and to ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Robitussin Nighttime Cough DM
Robitussin Nighttime Cough DM is used for cough, cough and nasal congestion
Dextromethorphan/guaifenesin/phenylephrine
Dextromethorphan/guaifenesin/phenylephrine systemic is used for cough and nasal congestion
Brompheniramine/dextromethorphan/pseudoephedrine
Brompheniramine/dextromethorphan/pseudoephedrine systemic is used for cough and nasal congestion
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.