Codeine/guaifenesin/phenylpropanolamine Interactions
There are 636 drugs known to interact with codeine/guaifenesin/phenylpropanolamine, along with 21 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 156 are major, 478 are moderate, and 2 are minor.
- View all 636 medications that may interact with codeine/guaifenesin/phenylpropanolamine
- View codeine/guaifenesin/phenylpropanolamine alcohol/food interactions (1)
- View codeine/guaifenesin/phenylpropanolamine disease interactions (21)
Most frequently checked interactions
View interaction reports for codeine / guaifenesin / phenylpropanolamine and the medicines listed below.
- Cymbalta (duloxetine)
- Hydrocet (acetaminophen / hydrocodone)
- Hydrocodone CP (chlorpheniramine / hydrocodone / phenylephrine)
- Lorcet 10 / 650 (acetaminophen / hydrocodone)
- Lortab (acetaminophen / hydrocodone)
- Nexium (esomeprazole)
- Nucynta (tapentadol)
- OxyContin (oxycodone)
- Percodan (aspirin / oxycodone)
- Tagamet (cimetidine)
- Trilipix (fenofibric acid)
- Vicodin (acetaminophen / hydrocodone)
- Vicoprofen (hydrocodone / ibuprofen)
- Xanax (alprazolam)
- Zydone (acetaminophen / hydrocodone)
Codeine/guaifenesin/phenylpropanolamine alcohol/food interactions
There is 1 alcohol/food interaction with codeine / guaifenesin / phenylpropanolamine.
Codeine/guaifenesin/phenylpropanolamine disease interactions
There are 21 disease interactions with codeine / guaifenesin / phenylpropanolamine which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- cardiovascular disease
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
- psychosis
- BPH
- diabetes
- glaucoma
Report options
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.