Can you take Aspercreme with Avatrombopag?
No drug interactions found, but 5 warnings to review for the following 2 drugs:
- Aspercreme (trolamine salicylate topical)
- avatrombopag
Drug interactions
There were no interactions found between Aspercreme and avatrombopag. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Food/lifestyle interactions
Moderate food/lifestyle interactions
Moderate:
avatrombopag Food/Lifestyle
Applies to: avatrombopag
Taking avatrombopag with food helps ensure consistent absorption of the medication into the blood stream.
You should take each dose of avatrombopag with food at the same time everyday.
Disease interactions
4 potential interactions Applies to: 4 conditions, including Thrombotic/Thromboembolic Disorder, Renal Dysfunction, History, Thrombotic/Thromboembolic Disorder, and Protein C Deficiency.
History, Thrombotic/Thromboembolic Disorder
Moderate:
avatrombopag
Avatrombopag has a moderate potential interaction with History, Thrombotic/Thromboembolic Disorder.
Thromboembolic complications may result from increases in platelet counts with TPO receptor agonists such as avatrombopag, lusutrombopag, and eltrombopag. Consider the potential for increased risk of thromboembolism when administering these medications to patients with known risk factors for thromboembolism, including genetic prothrombotic conditions (Factor V Leiden, Prothrombin 20210 A, Antithrombin deficiency or Protein C or S deficiency).
Protein C Deficiency
Moderate:
avatrombopag
Avatrombopag has a moderate potential interaction with Protein C Deficiency.
Thromboembolic complications may result from increases in platelet counts with TPO receptor agonists such as avatrombopag, lusutrombopag, and eltrombopag. Consider the potential for increased risk of thromboembolism when administering these medications to patients with known risk factors for thromboembolism, including genetic prothrombotic conditions (Factor V Leiden, Prothrombin 20210 A, Antithrombin deficiency or Protein C or S deficiency).
Renal Dysfunction
Moderate:
avatrombopag
Avatrombopag has a moderate potential interaction with Renal Dysfunction.
The effect of severe renal impairment (CrCl < 30 mL/min) including patients requiring hemodialysis on avatrombopag pharmacokinetics is unknown. Caution and monitoring is advised.
Thrombotic/Thromboembolic Disorder
Moderate:
avatrombopag
Avatrombopag has a moderate potential interaction with Thrombotic/Thromboembolic Disorder.
Thromboembolic complications may result from increases in platelet counts with TPO receptor agonists such as avatrombopag, lusutrombopag, and eltrombopag. Consider the potential for increased risk of thromboembolism when administering these medications to patients with known risk factors for thromboembolism, including genetic prothrombotic conditions (Factor V Leiden, Prothrombin 20210 A, Antithrombin deficiency or Protein C or S deficiency).
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Aspercreme
A total of 5 drugs are known to interact with Aspercreme.
- Aspercreme is in the drug class topical rubefacient.
- Aspercreme is used to treat the following conditions:
avatrombopag
A total of 98 drugs are known to interact with avatrombopag.
- Avatrombopag is in the drug class platelet-stimulating agents.
- Avatrombopag is used to treat the following conditions:
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.