Drug interactions between aluminum hydroxide / magnesium hydroxide / simethicone and Milk of Magnesia
|aluminum hydroxide/magnesium hydroxide/simethicone|
|Milk of Magnesia (magnesium hydroxide)|
Interactions between your drugs
aluminum hydroxide / magnesium hydroxide / simethicone
A total of 605 drugs (3162 brand and generic names) are known to interact with aluminum hydroxide / magnesium hydroxide / simethicone.
- Aluminum hydroxide / magnesium hydroxide / simethicone is in the drug class antacids.
- Aluminum hydroxide / magnesium hydroxide / simethicone is used to treat the following conditions:
Milk of Magnesia
- Milk of Magnesia is a member of the following drug classes: antacids, laxatives.
- Milk of Magnesia is used to treat the following conditions:
Drug and food interactions
aluminum hydroxide food
Applies to: aluminum hydroxide / magnesium hydroxide / simethicone
Citrate, or citric acid, can increase the absorption of aluminum hydroxide. This may lead to elevated blood levels of aluminum, particularly in individuals with reduced kidney function, since aluminum is primarily eliminated by the kidneys. Excess aluminum may deposit and cause problems in various tissues including bone, brain, heart, liver, muscles, and spleen. Over time, weak bones, bone pain, fractures, skeletal deformity, brain disorders, and anemia may develop. Talk to your doctor before using aluminum hydroxide if you have kidney impairment or are on hemodialysis. You should avoid or limit the consumption of citrate-containing foods and beverages (e.G., soft drinks, citrus fruits, fruit juices) during treatment with aluminum hydroxide. Be aware that some effervescent and dispersible drug formulations may also contain citrate and should be restricted as well. Even if you do not have kidney problems, it may be best to separate the dosing of aluminum hydroxide and citrate-containing products by 2 to 3 hours. Talk to a healthcare professional if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. When aluminum hydroxide is taken during enteral nutrition therapy (tube feeding), the tube may get clogged. Therefore, aluminum hydroxide should not be mixed with or given after high-protein tube feedings. The dose should be separated from the feeding by as much as possible, and the tube should be thoroughly flushed before administration of the dose.
Therapeutic duplication warnings
Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.
Stimulant and hyperosmotic laxatives
The recommended maximum number of medicines in the 'stimulant and hyperosmotic laxatives' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'stimulant and hyperosmotic laxatives' category:
- magnesium hydroxide (active ingredient in aluminum hydroxide/magnesium hydroxide/simethicone)
- magnesium hydroxide (active ingredient in Milk of Magnesia (magnesium hydroxide))
Note: The benefits of taking this combination of medicines may outweigh any risks associated with therapeutic duplication. This information does not take the place of talking to your doctor. Always check with your healthcare provider to determine if any adjustments to your medications are needed.
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.