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Purine nucleosides

What are Purine nucleosides

Purine nucleosides are antiviral agents that have selective activity against herpes simplex virus types 1 (cold sores) and 2 (genital herpes) and varicella zoster virus (chicken pox).

The purine nucleoside molecule is converted to a monophosphate by viral thymidine kinases. The monophosphate is then converted to diphosphate and then into a triphosphate form by cellular enzymes. The triphosphate form blocks the replication of viral DNA by inhibiting viral DNA polymerase and terminating the growing viral DNA chain.

Purine nucleosides are more potent against the viral enzymes than the host enzymes.

List of Purine nucleosides:

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Drug NameView by: Brand | Generic Reviews Avg. Ratings
ganciclovir systemic (Pro, More...)
0 reviews
   
10
valacyclovir systemic (Pro, More...)
323 reviews
   
9.0
famciclovir systemic (Pro, More...)
40 reviews
   
8.5
acyclovir systemic (Pro, More...)
118 reviews
   
8.3
valganciclovir systemic (Pro, More...)
1 review
   
8.0
ribavirin systemic (Pro, More...)
8 reviews
   
5.4
cidofovir systemic (Pro, More...)
0 reviewsAdd rating
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