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Potassium-sparing diuretics

What are Potassium-sparing diuretics

Potassium sparing diuretics increase diuresis by interfering with the sodium-potassium exchange in the distal convoluted tubule in the kidneys or act as an antagonist at the aldosterone receptor (they inhibit the sodium channels associated with the aldosterone-sensitive sodium pump). Aldosterone promotes sodium and water retention so by blocking its effects the potassium sparing diuretics (or aldosterone receptors antagonists) cause more sodium and water to pass into the collecting ducts, increasing diuresis.

Potassium sparing diuretics do not produce hypokalemia so can be used in conjunction with loop and thiazide diuretics.

List of Potassium-sparing diuretics:

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Drug Name DownUp( View by: Brand | Generic ) Reviews Ratings DownUp
spironolactone systemic (Pro, More...)
291 reviews
triamterene systemic (Pro, More...)
6 reviews
amiloride systemic (Pro, More...)
2 reviews