Ultravist Injection Dosage
Generic name: IOPROMIDE 240mg in 1mL
Dosage form: injection
Drug class: Non-ionic iodinated contrast media
Medically reviewed by Drugs.com. Last updated on Aug 14, 2025.
Important Dosage and Administration Information
- •
- ULTRAVIST is for intra-arterial or intravenous use only and must not be administered intrathecally.
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- Specific concentrations and presentations of ULTRAVIST are recommended for each type of imaging procedure.
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- Hydrate patients, as appropriate, prior to and following the administration of ULTRAVIST.
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- Individualize the volume, concentration, and injection rate of ULTRAVIST according to the specific dosing tables. Consider factors such as age, body weight, size of the vessel, and the rate of blood flow within the vessel; also consider extent of opacification required, structure(s) or area to be examined, disease processes affecting the patient, and equipment and technique to be employed.
- •
- Visually inspect ULTRAVIST for particulate matter and/or discoloration, whenever solution and container permit. Do not administer ULTRAVIST if particulate matter (including crystals) and/or discoloration is observed or if containers are defective.
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- Use aseptic technique for all handling and administration of ULTRAVIST.
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- Warm ULTRAVIST to body temperature before administration.
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- ULTRAVIST can be used with 0.9% Sodium Chloride Injection in a power injector suitable for simultaneous injection of contrast. However, do not mix or inject ULTRAVIST in intravenous administration lines containing other drugs or total nutritional admixtures.
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- Discard any unused portion remaining in the single-dose container following initial use.
Recommended Dosage for Intra-Arterial Procedures in Adults
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- The recommended doses for intra-arterial procedures in adults are shown in Table 1.
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- Inject at rates approximately equal to the flow rate in the vessel being injected.
|
Imaging Procedure |
Cerebral Arteriography |
Peripheral Arteriography |
Coronary Arteriography and |
Visceral Angiography and Aortography |
|
|
Concentration (mg Iodine per mL) |
300* |
300* |
370* |
370* |
|
|
Intra-Arterial Injection Sites |
Carotid Arteries |
3 mL to 12 mL |
- |
- |
- |
|
Vertebral Arteries |
4 mL to 12 mL |
||||
|
Aortic Arch Injection (four vessel study) |
20 mL to 50 mL |
||||
|
Subclavian or Femoral Artery |
- |
5 mL to 40 mL |
- |
- |
|
|
Aortic Bifurcation (distal runoff) |
25 mL to 50 mL |
||||
|
Right Coronary Artery |
- |
- |
3 mL to 14 mL |
- |
|
|
Left Coronary Artery |
3 mL to 14 mL |
||||
|
Left Ventricle |
30 mL to 60 mL |
||||
|
Aorta and Major Abdominal Branches |
- |
- |
- |
Individualize a volume approximately equal to the blood flow and related to the vascular and pathological characteristics of the specific vessels being studied. |
|
|
Maximum Total Dose |
150 mL |
250 mL |
225 mL |
225 mL |
|
*Use single-dose vials or pharmacy bulk package.
Recommended Dosage for Intravenous Procedures in Adults
Recommended doses for intravenous procedures in adults are shown in Table 2.
|
Imaging Procedure |
Excretory Urography |
Contrast Computed Tomography |
Contrast Mammography |
|
|
Concentration (mg Iodine per mL) |
300* |
300‡ |
370‡ |
300‡ or 370‡ |
|
Excretory Urography |
1 mL/kg body weight |
- |
- |
- |
|
CT of Head |
- |
50 mL to 200 mL |
41 mL to 162 mL |
- |
|
CT of Body - Single Phase Contrast Bolus Injection Rapid Infusion |
- |
50 mL to 200 mL 100 mL to 200 mL |
41 mL to 162 mL 81 mL to 162 mL |
- |
|
CT of Body – Multiple Phase Contrast |
- |
50 mL to 200 mL total volume Phase 1: 100% contrast, Phase 2: 20% to 60% contrast, using a power injector suitable for simultaneous injection of contrast and 0.9% Sodium Chloride Injection |
41 mL to 162 mL total volume Phase 1: 100% contrast, Phase 2: 20% to 60% contrast, using a power injector suitable for simultaneous injection of contrast and 0.9% Sodium Chloride Injection |
- |
|
Contrast Mammography |
- |
- |
- |
1.5 mL/kg body weight using a power injector at 2 mL/second to 4 mL/second |
|
Maximum Total Dose |
100 mL |
200 mL |
162 mL |
150 mL |
- *Use single-dose vials or pharmacy bulk package.
- ‡Use single-dose vials, pharmacy bulk package or imaging bulk package.
Recommended Dosage in Pediatric Patients Aged 2 Years and Older
The recommended doses in pediatric patients aged 2 years and older are shown in Table 3.
|
Imaging Procedure |
Intra-arterial |
Intravenous |
|
|
Cardiac Chambers and Related Arteries |
Excretory Urography |
Contrast Computerized Tomography |
|
|
Concentration (mg Iodine/mL) |
370* |
300* |
300‡ |
|
Volume (mL/kg body weight) |
1 to 2 |
1 to 2 |
1 to 2 |
|
Maximum Total Dose (mL/kg) |
4 |
3 |
3 |
- *Use single-dose vials or pharmacy bulk package.
- ‡Use single-dose vials, pharmacy bulk package or imaging bulk package.
Imaging Instruction for Contrast Mammography
For contrast mammography, use ULTRAVIST with a device that is cleared for dual-energy full field digital mammography.
Directions for Use of ULTRAVIST Pharmacy Bulk Package
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- ULTRAVIST Pharmacy Bulk Package (PBP) is not for direct infusion.
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- Perform the transfer of the PBP in a suitable work area, such as a laminar flow hood, utilizing aseptic technique.
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- Penetrate the container closure only one time, utilizing a suitable transfer device.
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- After initial puncture, use the contents of the PBP within 10 hours. Discard any unused portion
Directions for Use of ULTRAVIST Imaging Bulk Package
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- ULTRAVIST Imaging Bulk Package (IBP) is for intravenous use only.
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- ULTRAVIST IBP is for use only with an automated contrast injection system, contrast management system, or contrast media transfer set approved or cleared for use with this contrast agent in this IBP. Please see drug and device labeling for information on devices indicated for use with this IBP and techniques to help assure safe use.
- •
- The IBP is to be used only in a room designated for radiological procedures that involve intravascular administration of a contrast agent.
- •
- Using aseptic technique, penetrate the container closure of the IBP only one time with a suitable sterile component of the automated contrast injection system, contrast management system, or contrast media transfer set approved or cleared for use with this contrast agent in this IBP.
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- Once the IBP is punctured, do not remove it from the work area during the entire period of use. Maintain the bottle in an inverted position such that container contents are in continuous contact with the dispensing set.
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- After the container closure is punctured, if the integrity of the IBP and the delivery system cannot be assured through direct continuous supervision, discard the IBP and all associated disposables for the automated contrast injection system, contrast management system, or contrast media transfer set.
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- A maximum use time from initial puncture is 10 hours. Discard any unused portion remaining in IBP container.
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- Storage temperature of IBP after the closure has been entered should not exceed 25°C (77°F) with excursions permitted to 15°C to 30°C (59°F to 86°F); however, it is desirable that the contents be warmed to body temperature prior to injection.
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