Applies to the following strengths: 400 mg; 600 mg
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Arrhythmias
Initial dose: 400 mg orally every 8 hours.
Maintenance dose: 1200-1800 mg/day in 3 divided doses.
Renal Dose Adjustments
Some patients with renal impairment may be adequately treated with less than 1200 mg/day.
Liver Dose Adjustments
Some patients with hepatic impairment may be adequately treated with less than 1200 mg/day.
Patients who tolerate the t.i.d. regimen may be tried on a twice a day regimen with careful monitoring.
Tocainide is moderately dialyzable (20%-50%).
Doses beyond 2400 mg/day have been administered infrequently.