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Prednisolone / Sulfacetamide Sodium Ophthalmic Dosage

Medically reviewed on January 16, 2018.

Applies to the following strengths: 0.2%-10%; 0.25% sodium phosphate-10%; 0.5%-10%; 0.25%-10%

Usual Adult Dose for Uveitis

Suspension: Instill 2 drops into the conjunctival sac of the affected eye(s) every 4 hours during the day and at bedtime

Ointment: Apply small amount (about 1/2 inch ribbon) into the conjunctival sac of the affected eye(s) 3 to 4 times per day and once or twice at night

Solution: Instill 2 drops into the affected eye(s) every 4 hours

Comments:
-Care should be taken as to not discontinue therapy prematurely.
-If signs/symptoms fail to improve after 2 days of treatment, the patient should be re-evaluated.
-Withdrawal of therapy in chronic conditions should be carried out by gradually decreasing frequency of applications.
-Not more than 8 g of ointment or 20 mL of suspension or solution should be prescribed initially.

Use: For the treatment of steroid responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or risk of bacterial ocular infection exists

Usual Adult Dose for Bacterial Conjunctivitis

Suspension: Instill 2 drops into the conjunctival sac of the affected eye(s) every 4 hours during the day and at bedtime

Ointment: Apply small amount (about 1/2 inch ribbon) into the conjunctival sac of the affected eye(s) 3 to 4 times per day and once or twice at night

Solution: Instill 2 drops into the affected eye(s) every 4 hours

Comments:
-Care should be taken as to not discontinue therapy prematurely.
-If signs/symptoms fail to improve after 2 days of treatment, the patient should be re-evaluated.
-Withdrawal of therapy in chronic conditions should be carried out by gradually decreasing frequency of applications.
-Not more than 8 g of ointment or 20 mL of suspension or solution should be prescribed initially.

Use: For the treatment of steroid responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or risk of bacterial ocular infection exists

Usual Adult Dose for Keratitis

Suspension: Instill 2 drops into the conjunctival sac of the affected eye(s) every 4 hours during the day and at bedtime

Ointment: Apply small amount (about 1/2 inch ribbon) into the conjunctival sac of the affected eye(s) 3 to 4 times per day and once or twice at night

Solution: Instill 2 drops into the affected eye(s) every 4 hours

Comments:
-Care should be taken as to not discontinue therapy prematurely.
-If signs/symptoms fail to improve after 2 days of treatment, the patient should be re-evaluated.
-Withdrawal of therapy in chronic conditions should be carried out by gradually decreasing frequency of applications.
-Not more than 8 g of ointment or 20 mL of suspension or solution should be prescribed initially.

Use: For the treatment of steroid responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or risk of bacterial ocular infection exists

Usual Adult Dose for Keratoconjunctivitis

Suspension: Instill 2 drops into the conjunctival sac of the affected eye(s) every 4 hours during the day and at bedtime

Ointment: Apply small amount (about 1/2 inch ribbon) into the conjunctival sac of the affected eye(s) 3 to 4 times per day and once or twice at night

Solution: Instill 2 drops into the affected eye(s) every 4 hours

Comments:
-Care should be taken as to not discontinue therapy prematurely.
-If signs/symptoms fail to improve after 2 days of treatment, the patient should be re-evaluated.
-Withdrawal of therapy in chronic conditions should be carried out by gradually decreasing frequency of applications.
-Not more than 8 g of ointment or 20 mL of suspension or solution should be prescribed initially.

Use: For the treatment of steroid responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or risk of bacterial ocular infection exists

Usual Adult Dose for Blepharitis

Suspension: Instill 2 drops into the conjunctival sac of the affected eye(s) every 4 hours during the day and at bedtime

Ointment: Apply small amount (about 1/2 inch ribbon) into the conjunctival sac of the affected eye(s) 3 to 4 times per day and once or twice at night

Solution: Instill 2 drops into the affected eye(s) every 4 hours

Comments:
-Care should be taken as to not discontinue therapy prematurely.
-If signs/symptoms fail to improve after 2 days of treatment, the patient should be re-evaluated.
-Withdrawal of therapy in chronic conditions should be carried out by gradually decreasing frequency of applications.
-Not more than 8 g of ointment or 20 mL of suspension or solution should be prescribed initially.

Use: For the treatment of steroid responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or risk of bacterial ocular infection exists

Usual Pediatric Dose for Uveitis

6 years or older:
-Suspension: Instill 2 drops into the conjunctival sac of the affected eye(s) every 4 hours during the day and at bedtime
-Ointment: Apply small amount (about 1/2 inch ribbon) into the conjunctival sac of the affected eye(s) 3 to 4 times per day and once or twice at night
-Solution: Instill 2 drops into the affected eye(s) every 4 hours

Comments:
-Care should be taken as to not discontinue therapy prematurely.
-If signs/symptoms fail to improve after 2 days of treatment, the patient should be re-evaluated.
-Withdrawal of therapy in chronic conditions should be carried out by gradually decreasing frequency of applications.
-Not more than 8 g of ointment or 20 mL of suspension or solution should be prescribed initially.

Use: For the treatment of steroid responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or risk of bacterial ocular infection exists

Usual Pediatric Dose for Bacterial Conjunctivitis

6 years or older:
-Suspension: Instill 2 drops into the conjunctival sac of the affected eye(s) every 4 hours during the day and at bedtime
-Ointment: Apply small amount (about 1/2 inch ribbon) into the conjunctival sac of the affected eye(s) 3 to 4 times per day and once or twice at night
-Solution: Instill 2 drops into the affected eye(s) every 4 hours

Comments:
-Care should be taken as to not discontinue therapy prematurely.
-If signs/symptoms fail to improve after 2 days of treatment, the patient should be re-evaluated.
-Withdrawal of therapy in chronic conditions should be carried out by gradually decreasing frequency of applications.
-Not more than 8 g of ointment or 20 mL of suspension or solution should be prescribed initially.

Use: For the treatment of steroid responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or risk of bacterial ocular infection exists

Usual Pediatric Dose for Keratitis

6 years or older:
-Suspension: Instill 2 drops into the conjunctival sac of the affected eye(s) every 4 hours during the day and at bedtime
-Ointment: Apply small amount (about 1/2 inch ribbon) into the conjunctival sac of the affected eye(s) 3 to 4 times per day and once or twice at night
-Solution: Instill 2 drops into the affected eye(s) every 4 hours

Comments:
-Care should be taken as to not discontinue therapy prematurely.
-If signs/symptoms fail to improve after 2 days of treatment, the patient should be re-evaluated.
-Withdrawal of therapy in chronic conditions should be carried out by gradually decreasing frequency of applications.
-Not more than 8 g of ointment or 20 mL of suspension or solution should be prescribed initially.

Use: For the treatment of steroid responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or risk of bacterial ocular infection exists

Usual Pediatric Dose for Keratoconjunctivitis

6 years or older:
-Suspension: Instill 2 drops into the conjunctival sac of the affected eye(s) every 4 hours during the day and at bedtime
-Ointment: Apply small amount (about 1/2 inch ribbon) into the conjunctival sac of the affected eye(s) 3 to 4 times per day and once or twice at night
-Solution: Instill 2 drops into the affected eye(s) every 4 hours

Comments:
-Care should be taken as to not discontinue therapy prematurely.
-If signs/symptoms fail to improve after 2 days of treatment, the patient should be re-evaluated.
-Withdrawal of therapy in chronic conditions should be carried out by gradually decreasing frequency of applications.
-Not more than 8 g of ointment or 20 mL of suspension or solution should be prescribed initially.

Use: For the treatment of steroid responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or risk of bacterial ocular infection exists

Usual Pediatric Dose for Blepharitis

6 years or older:
-Suspension: Instill 2 drops into the conjunctival sac of the affected eye(s) every 4 hours during the day and at bedtime
-Ointment: Apply small amount (about 1/2 inch ribbon) into the conjunctival sac of the affected eye(s) 3 to 4 times per day and once or twice at night
-Solution: Instill 2 drops into the affected eye(s) every 4 hours

Comments:
-Care should be taken as to not discontinue therapy prematurely.
-If signs/symptoms fail to improve after 2 days of treatment, the patient should be re-evaluated.
-Withdrawal of therapy in chronic conditions should be carried out by gradually decreasing frequency of applications.
-Not more than 8 g of ointment or 20 mL of suspension or solution should be prescribed initially.

Use: For the treatment of steroid responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or risk of bacterial ocular infection exists

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Safety and efficacy have not been established in patients younger than 6 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-Suspension: Shake well before use.

Storage requirements:
-Solution and suspension: Store in an upright position; protect from light and freezing; avoid use if solution has darkened.

Monitoring:
-Ocular: Eyelid cultures and tests to determine susceptibility of organisms to sulfacetamide may be indicated if signs/symptoms persist or recur despite recommended course of treatment.

Patient advice:
-Discontinue use and contact your physician if inflammation or pain persists longer than 48 hours or becomes aggravated.
-Avoid allowing the tip of the dropper/tube to touch they eyelid or to any surface as this may cause contamination.
-Avoid wearing of contact lenses while using the suspension.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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