Nemolizumab Dosage

Medically reviewed by Drugs.com. Last updated on Oct 7, 2024.

Usual Adult Dose for Prurigo Nodularis

Patients weighing less than 90 kg: Initial subcutaneous (SC) dose of 60 mg (two 30 mg injections), followed by 30 mg given every 4 weeks
Patients weighing 90 kg or more: Initial SC dose of 60 mg (two 30 mg injections), followed by 60 mg given every 4 weeks:

Comments:

• Complete all age-appropriate vaccinations following immunization guidelines before starting treatment with this drug.

Use: Treatment of adults with prurigo nodularis

Renal Dose Adjustments

• Mild and Moderate Renal Dysfunction: No adjustment recommended
• Severe Renal Dysfunction: Data not available

Liver Dose Adjustments

• Mild and Moderate Liver Dysfunction: No adjustment recommended
• Severe Liver Dysfunction: Data not available

Precautions

CONTRAINDICATIONS:

• Known hypersensitivity to the active ingredient or to any of the excipients

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• This drug is administered by SC injection.
• Use under the guidance of a health care provider. Prior to the first injection patients or their caregivers should be trained in the proper preparation and administration of this drug. Patients can self-inject after receiving training.
• For the first dose, administer the two injections on different body injection sites. The SC injection can be administered into the front upper thigh or abdomen (except for the 2 inches around the navel). Injection in the upper arm should be performed by a health professional or caregiver.
• Alternate injection sites, and do not inject in skin that is inflamed, swollen, tender or has bruises, scars or open wounds.
• If a dose is missed, administer as soon as possible and thereafter resume regular scheduled time.
• Consult the manufacturer product information for additional administration instructions.

Storage requirements:

• Each carton contains 1 single-dose prefilled pen which should be refrigerated at 36F to 46F (2C to 8C) in the original carton to protect from light until the expiration date. Do not freeze.
• Do not expose to heat or sunlight.
• Write the date in the prefilled pen once it is first removed from the refrigerator, and do not use after 90 days or beyond the expiration date (whichever comes first).
• Alternatively, store at room temperature (up to 77F [25C]) for up to 90 days.

Preparation techniques:

• Consult the manufacturer product information for injection preparation instructions.

General:

• Report suspected adverse reactions to Galderma Laboratories at 1-866-735-4137 or the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Monitor:

• Signs or symptoms of hypersensitivity
• Signs or symptoms of adverse reactions

Patient advice:

• Read the US FDA-approved patient labeling (Patient Information and Instructions for Use).
• Seek immediate attention if you experience any symptoms of hypersensitivity.
• Inform your health care provider that you are taking this drug prior to any vaccination.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer