Methysergide Maleate Dosage
Applies to the following strengths: 2 mg
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Cluster Headache
For the prophylaxis of cluster headaches: 4 to 8 mg daily orally in divided doses with meals.
Usual Adult Dose for Migraine
For the prophylaxis of migraine headaches: 4 to 8 mg daily orally in divided doses with meals.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Dialysis
Data not available
Other Comments
There must be a drug-free interval of 3 to 4 weeks after every 6 month course of treatment.
If after a 3 week trial period, efficacy has not been demonstrated, continued administration is unlikely to be beneficial.
The protective effect of methysergide reportedly develops in 1 to 2 days and persists 1 to 2 days after the drug is discontinued.
Patients who take ergotamine for extended periods of time may become dependent on it and require progressively increasing doses for relief of vascular headaches and for prevention of dysphoria effects which follow withdrawal.
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