Meningococcal Group Acwy Conjugate-Group B Vaccine (Cvx 328) Dosage

Medically reviewed by Drugs.com. Last updated on Jul 15, 2025.

Usual Adult Dose for Meningococcal Meningitis Prophylaxis

Up to 25 years of age: 0.5 mL IM for 2 doses, administered 6 months apart

Use: Active immunization to prevent invasive disease caused by Neisseria meningitidis serogroups A, B, C, W, and Y

Usual Pediatric Dose for Meningococcal Meningitis Prophylaxis

10 years of age and older: 0.5 mL IM for 2 doses, administered 6 months apart

Use: Active immunization to prevent invasive disease caused by N meningitidis serogroups A, B, C, W, and Y

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:

• Known history of severe allergic reactions (e.g., anaphylaxis) to the active component, other diphtheria toxoid-containing vaccines, or any of the ingredients
• History of a severe allergic reaction after a previous dose of this vaccine

Safety and efficacy have not been established in patients younger than 10 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• Administer IM in the deltoid muscle of the upper arm.
• Use immediately after reconstitution.

Storage requirements:

• Store refrigerated between 2C to 8C (36F to 46F); protect from light.
• Do not freeze. Discard if the vaccine has been frozen.

Reconstitution/preparation techniques:

• Do not dilute.
• Consult the Fact Sheet for Health Care Providers.

General:

• This vaccine may contain white or translucent particulates.

Patient advice:

• Read the US FDA-approved patient information.
• To report suspected adverse reactions, contact the Vaccine Adverse Event Reporting System (VAERS): https://vaers.hhs.gov

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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