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Mebrofenin Dosage

Applies to the following strengths: 45 mg

Usual Adult Dose for Diagnostic

74 to 185 mBq (2 to 5 mCi) intravenously

Comments: Measure the patient dose by a suitable radioactivity calibration system immediately prior to administration.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

If the patient's serum bilirubin level is greater than 1.5 mg/dL, increase the dose to 111 to 370 MBq (3 to 10 mCi).

Precautions

Consult WARNINGS section for dosing related precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-Patient should fast for at least 4 hours prior to administration. False positives (non-visualization) may result if the gallbladder has been emptied by food ingestion.
-Allow an interval of at least 24 hours before repeat examination.
-Contents of the reaction vial are intended only for use in the preparation of technetium Tc99m mebrofenin. Do not administer directly to the patient.
-Inspect for particulate matter and discoloration prior to administration.
-Use within 18 hours of reconstitution.

Storage requirements:
-Store the kit as supplied at 20C to 25C (68F to 77F) prior to and following reconstitution.

Reconstitution/preparation techniques:
-For information about the preparation of mebrofenin, see the manufacturer's product information.

General:
- The reagent kit is approved for distribution to those licensed by the U.S. Nuclear Regulatory Commission to use byproduct material identified in 10 CFR 35.200 or an equivalent license.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.