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Konvomep Dosage

Generic name: OMEPRAZOLE 2mg in 1mL; SODIUM BICARBONATE 84mg in 1mL
Dosage form: oral suspension
Drug class: Proton pump inhibitors

Medically reviewed by Last updated on Aug 30, 2023.

Important Administration Instructions

KONVOMEP is a kit of two bottles: one bottle containing omeprazole powder and one bottle of diluent containing sodium bicarbonate.
KONVOMEP is for reconstitution by a healthcare provider for use in adults.
After reconstitution, each mL of KONVOMEP contains 2 mg of omeprazole and 84 mg of sodium bicarbonate.
Take the sodium content of KONVOMEP into consideration when prescribing this product [see Warnings and Precautions (5.3)].
Recommended doses throughout the labeling are based upon the omeprazole component of KONVOMEP.

Dosage Regimen

The recommended dosage regimen in adults of KONVOMEP by indication is summarized in Table 1. Recommended dosage is based upon the omeprazole content of KONVOMEP.

Table 1: Recommended Dosage Regimen of KONVOMEP for Adults by Indication
Indication Recommended Dosage Treatment Duration

Treatment of Benign Gastric Ulcer

40 mg once daily

4 to 8 weeks

Reduction of Risk of Upper GI Bleeding in Critically Ill Patients

40 mg initially; followed by 40 mg 6 to 8 hours later; and 40 mg once daily thereafter

14 days

Preparation and Administration

Preparation of Reconstituted Suspension by a Healthcare Provider Prior to Dispensing

Hold the neck of the bottle containing the omeprazole powder and tap all four of the bottom edges on a hard surface to loosen the powder.
Shake the diluent containing sodium bicarbonate for a few seconds. Open the diluent bottle and transfer about one-third of the contents into the bottle containing omeprazole powder, replace the omeprazole powder cap, and shake the bottle vertically for approximately 30 seconds.
Add a second one-third of the diluent into the omeprazole powder bottle and shake the bottle vigorously for approximately 30 seconds.
Add the remaining diluent into the omeprazole powder bottle. Allow diluent to drain into the omeprazole powder bottle for 10 seconds and shake the omeprazole bottle vigorously for approximately 30 seconds.
The reconstituted suspension contains 40 mg of omeprazole per 20 mL and should be pink to red and hazy.
Instruct the patient to shake the reconstituted suspension well before each use. Use an oral dosing device that measures the appropriate volume.

Nasogastric or Orogastric Tube Administration (8 French or larger)

If KONVOMEP is administered via nasogastric or orogastric tube, suspend enteral feeding approximately 3 hours before and 1 hour after administration of KONVOMEP.

Reconstitute KONVOMEP according to the steps for preparation provided above.
Use a catheter or oral tip syringe to administer KONVOMEP through the nasogastric or orogastric tube.
Shake the bottle well prior to dispensing 20 mL of KONVOMEP into the syringe.
Immediately inject the medication through the nasogastric or orogastric tube into the stomach.
Refill the syringe with 20 mL of water.
Flush any remaining medication from the nasogastric or orogastric tube into the stomach.

Storage of Reconstituted Suspension

Store the reconstituted KONVOMEP suspension under refrigerated conditions 2°C to 8°C (36°F to 45°F) for up to 30 days.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.