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Iopromide Dosage

Applies to the following strengths: 150 mg/mL; 240 mg/mL; 300 mg/mL; 370 mg/mL

Usual Adult Dose for Intra-arterial Digital Subtraction Angiography

Iopromide 150 mg I/mL: Carotid Arteries: 6 to 10 mL; Vertebral Arteries 4 to 8 mL; Aorta: 20 to 50 mL; Abdominal Aorta 2 to 20 mL. The maximum total recommended dose is 250 mL.

Usual Adult Dose for Cerebral Arteriography

Iopromide 300 mg I/mL: Carotid Arteries: 3 to 12 mL; Vertebral Arteries 4 to 12 mL; Aortic Arch Injection (4 vessel study): 20 to 50 mL. The maximum total recommended dose is 150 mL.

Usual Adult Dose for Peripheral Arteriography

Iopromide 300 mg I/mL: Subclavian or Femoral Artery: 5 to 40 mL; Aortic Bifurcation (distal runoff): 25 to 50 mL. The maximum total recommended dose is 250 mL.

Usual Adult Dose for Coronary Arteriography

Iopromide 370 mg I/mL: Right or Left Coronary Artery: 3 to 14 mL; Left Ventricle: 30 to 60 mL. The maximum total recommended dose is 225 mL.

Usual Adult Dose for Left Ventriculography

Iopromide 370 mg I/mL: Right or Left Coronary Artery: 3 to 14 mL; Left Ventricle: 30 to 60 mL. The maximum total recommended dose is 225 mL.

Usual Adult Dose for Venography

Peripheral Venography:
Iopromide 240 mg I/mL: Inject the minimum volume necessary to visualize satisfactorily the structures under examination. Do not exceed 250 mL as total dose for the procedure.

Usual Adult Dose for Computed Tomography

Contrast Computed Tomography:
Iopromide 300 mg I/mL: Head: 50 to 200 mL; Body, bolus injection: 50-200 mL; Body, rapid infusion: 100-200 mL. The maximum total recommended dose is 200 mL.

Iopromide 370 mg I/mL: Head: 41 to 162 mL; Body, bolus injection: 41-162 mL; Body, rapid infusion: 81-162 mL. The maximum total recommended dose is 162 mL.

Usual Adult Dose for Urography

Excretory urography: Iopromide 300 mg I/mL: 300 mg I/kg body weight. The maximum total recommended dose is 100 mL.

Usual Pediatric Dose for Computed Tomography

Contrast Computerized Tomography or Excretory Urography (300 mg I/mL): Inject 1 to 2 mL/kg intravenously. Do not exceed 3 mL/kg as total dose.

Usual Pediatric Dose for Urography

Contrast Computerized Tomography or Excretory Urography (300 mg I/mL): Inject 1 to 2 mL/kg intravenously. Do not exceed 3 mL/kg as total dose.

Usual Pediatric Dose for Coronary Arteriography

Cardiac chambers and related arteries (370 mg I/mL): Inject 1 to 2 milliliters per kilogram (mL/kg) intra-arterially. Do not exceed 4 mL/kg as total dose.

Renal Dose Adjustments

Renal dysfunction: Use with caution. The lowest necessary dose should be used.

Liver Dose Adjustments

Data not available

Dose Adjustments

Carefully individualize the volume and concentration of iopromide to be used for a vascular procedure, according to the specific dosing guidelines. Adjust the dose accounting for factors such as age, body weight, size of the vessel and the rate of blood flow within the vessel. Also consider the extent of opacification required, structure(s) or area to be examined, disease processes affecting the patient, and equipment and technique to be employed.

Iopromide should be used at the lowest effective dose in order to minimize adverse effects. The efficacy of iopromide at doses below those recommended has not been established.

The maximum recommended total dose of iodine in adults is 86 grams; a maximum recommended total dose of iodine has not been established for pediatric patients.

Precautions

US BOXED WARNING:
NOT FOR INTRATHECAL USE:
Inadvertent intrathecal administration may cause death, convulsions, cerebral hemorrhage, coma, paralysis, arachnoiditis, acute renal failure, cardiac arrest, seizures, rhabdomyolysis, hyperthermia, and brain edema.

Safety and efficacy have not been established in patients younger than 2 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Hydrate patients adequately prior to and following the administration of iopromide.

Warming iopromide to body temperature shortly before administration may help improve tolerability and ease of injection.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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