Hemangeol Dosage
Generic name: PROPRANOLOL HYDROCHLORIDE 4.28mg in 1mL
Dosage form: oral solution
Drug classes: Group II antiarrhythmics, Non-cardioselective beta blockers
Medically reviewed by Drugs.com. Last updated on Nov 6, 2024.
Initiate treatment at ages 5 weeks to 5 months.
The recommended starting dose of HEMANGEOL is 0.15 mL/kg (0.6 mg/kg) (see Table 1) twice daily, taken at least 9 hours apart. After 1 week, increase the daily dose to 0.3 mL/kg (1.1 mg/kg) twice daily. After 2 weeks of treatment, increase the dose to 0.4 mL/kg (1.7 mg/kg) twice daily and maintain this for 6 months. Readjust the dose periodically as the child’s weight increases.
To reduce the risk of hypoglycemia, administer HEMANGEOL orally during or right after a feeding. Skip the dose if the child is not eating or is vomiting .
Monitor heart rate and blood pressure for 2 hours after HEMANGEOL initiation or dose increases.
If hemangiomas recur, treatment may be re-initiated .
HEMANGEOL is supplied with an oral dosing syringe for administration. Administration directly into the child’s mouth is recommended. Nevertheless, if necessary, the product may be diluted in a small quantity of milk or fruit juice, given in a baby’s bottle.
Table 1. Dose Titration According to Weight
| Week 1 |
Week 2 |
Week 3 (maintenance) |
|
|
Weight (kg) |
Volume administered |
Volume administered |
Volume administered |
| twice a day | twice a day | twice a day | |
|
2 to <2.5 |
0.3 mL |
0.6 mL |
0.8 mL |
|
2.5 to <3 |
0.4 mL |
0.8 mL |
1 mL |
|
3 to <3.5 |
0.5 mL |
0.9 mL |
1.2 mL |
|
3.5 to <4 |
0.5 mL |
1.1 mL |
1.4 mL |
|
4 to <4.5 |
0.6 mL |
1.2 mL |
1.6 mL |
|
4.5 to <5 |
0.7 mL |
1.4 mL |
1.8 mL |
|
5 to <5.5 |
0.8 mL |
1.5 mL |
2 mL |
|
5.5 to <6 |
0.8 mL |
1.7 mL |
2.2 mL |
|
6 to <6.5 |
0.9 mL |
1.8 mL |
2.4 mL |
|
6.5 to <7 |
1 mL |
2 mL |
2.6 mL |
|
7 to <7.5 |
1.1 mL |
2.1 mL |
2.8 mL |
|
7.5 to <8 |
1.1 mL |
2.3 mL |
3 mL |
|
8 to <8.5 |
1.2 mL |
2.4 mL |
3.2 mL |
|
8.5 to <9 |
1.3 mL |
2.6 mL |
3.4 mL |
|
9 to <9.5 |
1.4 mL |
2.7 mL |
3.6 mL |
|
9.5 to <10 |
1.4 mL |
2.9 mL |
3.8 mL |
|
10 to <10.5 |
1.5 mL |
3 mL |
4 mL |
|
10.5 to <11 |
1.6 mL |
3.2 mL |
4.2 mL |
|
11 to <11.5 |
1.7 mL |
3.3 mL |
4.4 mL |
|
11.5 to <12 |
1.7 mL |
3.5 mL |
4.6 mL |
| 12 to <12.5 | 1.8 mL | 3.6 mL | 4.8 mL |
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