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Echothiophate Iodide Ophthalmic Dosage

Medically reviewed by Last updated on Nov 1, 2021.

Applies to the following strengths: 0.03%; 0.06%; 0.125%; 0.25%

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Intraocular Hypertension

Instill 1 drop in the affected eye(s) twice a day, in the morning and at bedtime


  • If the tension fails to remain at an acceptable level on the usual regimen, a change in therapy is indicated.
  • The once a day dose or one of the twice a day doses should always be instilled just before bedtime to avoid inconvenience due to the miosis.
  • Twice a day dosing is preferred to once a day in order to maintain as smooth a diurnal tension curve as possible.

Use: Reduction of elevated intraocular pressure (IOP)

Usual Pediatric Dose for Strabismus

Diagnosis of accommodative esotropia: One drop may be instilled once a day in both eyes before bedtime, for a period of two or three weeks.


  • Favorable response will usually be noted within a few hours.

Maintenance of accommodation esotropia: Instill 1 drop in both eyes once a day or every other day depending on satisfactory results.

  • The maximum usually recommended dosage is one drop once a day, although more intensive therapy has been used for short periods.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

  • A once a day or every other day dose has been used with satisfactory results.



  • Hypersensitivity to any of the ingredients
  • Active uveal inflammation
  • Most cases of angle-closure glaucoma without iridectomy, due to the possibility of increasing angle block.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments

Administration advice:

  • Digital compression of the nasolacrimal ducts for a minute or two following instillation to minimize drainage into the nasal chamber is recommended.

Storage requirements:
  • Prior to reconstitution: Refrigerate at 2C to 8 C.
  • After reconstitution: Store at room temperature at approximately 25 C. Do not refrigerate. Discard any unused solution after 4 weeks.

Reconstitution/preparation techniques:
  • The manufacturer product information should be consulted.

Patient advice:
  • Tolerance may occasionally develop after prolonged use.
  • Consider surgery if deviation recurs after about a year or two after gradually withdrawing this drug.
  • Wash hands before and after instillation.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.