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Echothiophate Iodide Ophthalmic Dosage

Medically reviewed by Last updated on Oct 30, 2020.

Applies to the following strengths: 0.03%; 0.06%; 0.125%; 0.25%

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Intraocular Hypertension

Instill 1 drop in the affected eye(s) twice a day, in the morning and at bedtime

-If the tension fails to remain at an acceptable level on the usual regimen, a change in therapy is indicated.
-The once a day dose or one of the twice a day doses should always be instilled just before bedtime to avoid inconvenience due to the miosis.
-Twice a day dosing is preferred to once a day in order to maintain as smooth a diurnal tension curve as possible.

Use: Reduction of elevated intraocular pressure (IOP)

Usual Pediatric Dose for Strabismus

Diagnosis of accommodative esotropia: One drop may be instilled once a day in both eyes before bedtime, for a period of two or three weeks.

-Favorable response will usually be noted within a few hours.

Maintenance of accommodation esotropia: Instill 1 drop in both eyes once a day or every other day depending on satisfactory results.

-The maximum usually recommended dosage is one drop once a day, although more intensive therapy has been used for short periods.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

-A once a day or every other day dose has been used with satisfactory results.


-Hypersensitivity to any of the ingredients
-Active uveal inflammation
-Most cases of angle-closure glaucoma without iridectomy, due to the possibility of increasing angle block.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments

Administration advice:
-Digital compression of the nasolacrimal ducts for a minute or two following instillation to minimize drainage into the nasal chamber is recommended.

Storage requirements:
-Prior to reconstitution: Refrigerate at 2C to 8 C.
-After reconstitution: Store at room temperature at approximately 25 C. Do not refrigerate. Discard any unused solution after 4 weeks.

Reconstitution/preparation techniques:
-The manufacturer product information should be consulted.

Patient advice:
-Tolerance may occasionally develop after prolonged use.
-Consider surgery if deviation recurs after about a year or two after gradually withdrawing this drug.
-Wash hands before and after instillation.

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