Complera Dosage
Generic name: emtricitabine 200mg, rilpivirine hydrochloride 25mg, tenofovir disoproxil fumarate 300mg
Dosage form: tablet, film coated
Drug class: Antiviral combinations
Medically reviewed by Drugs.com. Last updated on Sep 24, 2024.
Testing Prior to Initiation and During Treatment with COMPLERA
Prior to or when initiating COMPLERA, test patients for hepatitis B virus infection.
Prior to initiation of COMPLERA, and during treatment with COMPLERA, on a clinically appropriate schedule, assess serum creatinine, estimated creatinine clearance, urine glucose and urine protein in all patients. In patients with chronic kidney disease, also assess serum phosphorus.
Recommended Dosage
COMPLERA is a three-drug fixed dose combination product containing 200 mg of emtricitabine (FTC), 25 mg of rilpivirine (RPV), and 300 mg of tenofovir disoproxil fumarate (TDF). The recommended dosage of COMPLERA in adult and pediatric patients weighing at least 35 kg is one tablet taken orally once daily with food.
Recommended Dosage During Pregnancy
For pregnant patients who are already on COMPLERA prior to pregnancy and are virologically suppressed (HIV-1 RNA less than 50 copies per mL), one tablet of COMPLERA taken once daily may be continued. Lower exposures of rilpivirine, a component of COMPLERA, were observed during pregnancy, therefore viral load should be monitored closely.
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Further information
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