Acoramidis Dosage

Medically reviewed by Drugs.com. Last updated on Jan 14, 2025.

Usual Adult Dose for Hypertrophic Cardiomyopathy

Recommended dosage: 712 mg orally twice daily

Comments:

• Can be administered with or without food

Use: For the treatment of the cardiomyopathy of wild-type or variant transthyretin-mediated amyloidosis (ATTR-CM) in adults to reduce cardiovascular death and cardiovascular-related hospitalization.

Usual Adult Dose for Amyloidogenic Transthyretin Amyloidosis

Recommended dosage: 712 mg orally twice daily

Comments:

• Can be administered with or without food

Use: For the treatment of the cardiomyopathy of wild-type or variant transthyretin-mediated amyloidosis (ATTR-CM) in adults to reduce cardiovascular death and cardiovascular-related hospitalization.

Renal Dose Adjustments

No adjustment recommended.

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS: None

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• Take tablets with or without food.
• Swallow whole; do not cut, crush, or chew tablets.

Storage requirements:

• Store at controlled room temperature 20C to 25C (68F to 77F), with excursions permitted to 15C to 30C (59F to 86F)
• Store in original blister card to protect from moisture

General:

• Report suspected adverse reactions to BridgeBio Pharma Inc. at 1-844-550-2246 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
• Report pregnancies to the BridgeBio reporting line at 1-844-550-2246.

Patient advice:

• Read the US FDA-approved patient labeling (Patient Information).
• Patients of childbearing potential: Notify health care provider of a known or suspected pregnancy.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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