Briumvi Disease Interactions
There are 3 disease interactions with Briumvi (ublituximab).
Ublituximab (applies to Briumvi) hepatitis
Major Potential Hazard, Moderate plausibility. Applicable conditions: Infectious Hepatitis
The use of ublituximab is contraindicated in patients with active hepatitis B virus infection.
Ublituximab (applies to Briumvi) infections
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Infection - Bacterial/Fungal/Protozoal/Viral
Serious, including life-threatening and fatal infections, have occurred in patients using ublituximab. Delay treatment in patients with an active infection until the infection is resolved. Vaccination with live-attenuated or
live vaccines is not recommended during treatment with ublituximab and after discontinuation, until B-cell repletion.
Ublituximab (applies to Briumvi) renal/hepatic
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction, Liver Disease
The effect of moderate to severe renal impairment or moderate to severe hepatic impairment on the pharmacokinetics of ublituximab is unknown.
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Briumvi drug interactions
There are 422 drug interactions with Briumvi (ublituximab).
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
