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Protropin Disease Interactions

There are 2 disease interactions with Protropin (somatrem).

Moderate

Growth hormone (applies to Protropin) diabetes

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Diabetes Mellitus

The use of growth hormone has been associated with resistance to insulin. Patients with diabetes mellitus or impaired glucose tolerance should be observed closely during therapy. The dose of antihyperglycemic drugs (insulin or oral/injectable agents) may require adjustment.

References (3)
  1. (2001) "Product Information. Nutropin (somatropin)." Genentech
  2. (2001) "Product Information. Protropin (somatrem)." Genentech
  3. (2021) "Product Information. Skytrofa (lonapegsomatropin)." Ascendis Pharma, Inc.
Moderate

Growth hormone (applies to Protropin) hypothyroidism

Moderate Potential Hazard, Moderate plausibility.

The use of growth hormone has been associated with the development of hypothyroidism. Patients should be monitored baseline and periodically for adequate thyroid function. Inadequate treatment of hypothyroidism may inhibit the optimal response to growth hormone.

References (3)
  1. (2001) "Product Information. Nutropin (somatropin)." Genentech
  2. (2001) "Product Information. Protropin (somatrem)." Genentech
  3. (2021) "Product Information. Skytrofa (lonapegsomatropin)." Ascendis Pharma, Inc.

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Protropin drug interactions

There are 437 drug interactions with Protropin (somatrem).

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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